China Factory Direct
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| CAS number | 14091-15-7 |
| Product name | 4-BROMO-DL-PHENYLALANINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Non-natural amino acid building block for synthesizing peptide-based drugs | Introduction of p-bromophenylalanine residues in solid-phase peptide synthesis (SPPS) for structure–activity relationship studies or as sites for subsequent coupling reactions (e.g., Suzuki coupling) |
| Biochemistry | Protein engineering and probe construction | Site-specific modification via the bromine atom on the aromatic ring—e.g., palladium-catalyzed cross-coupling to introduce fluorophores, biotin, or other functional groups |
| Organic Synthesis | Intermediate for synthesizing complex aromatic compounds | Participation as an aryl halide in transition metal-catalyzed cross-coupling reactions—including Suzuki, Heck, and Sonogashira—to construct C–C or C–heteroatom bonds |
| Agrochemical R&D | Structural motif for potential active molecules | Used in the design and synthesis of novel pesticide lead compounds with targeted biological activity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., bromobenzene, phenylalanine, dibromo analogs) using gradient HPLC with UV detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the reaction of iodine with water in a pyridine-methanol solvent system. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after incineration at 700-800 C and weighing of residual residue. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions following aqueous extraction and filtration. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a polarimeter at 20 C with sodium D-line (589 nm) to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change in a calibrated capillary tube. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying | Weight loss determination after drying at 105 C under vacuum or air for specified time. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Hydrogen ion activity measured using calibrated glass electrode in a 1% w/v aqueous suspension. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered light intensity from dispersed particles to calculate volume-based size distribution. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic mesophilic microorganisms and absence testing for specified pathogens per pharmacopeial methods. |
| Test Item | Specification |
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| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (HPLC) |
| Melting Point | 245–249 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Optical Rotation | -15.0 to -19.0 ° (c=1, 1M HCl) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.