alpha-Bromo-2-chlorophenylacetic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 141109-25-3 |
| Product name | alpha-Bromo-2-chlorophenylacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for alpha-Bromo-2-chlorophenylacetic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk alpha-Bromo-2-chlorophenylacetic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of alpha-Bromo-2-chlorophenylacetic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the anticoagulant drug dabigatran etexilate | Used in multistep organic synthesis to construct the benzimidazole core of dabigatran etexilate via nucleophilic substitution, reduction, or coupling reactions |
| Chemical Synthesis | Preparation of other chlorinated and brominated phenylacetic acid derivatives | Functional group introduction via halogen exchange, metal-catalyzed coupling (e.g., Suzuki or Negishi reactions), or esterification/amidation |
Manufacturing Quality Control of alpha-Bromo-2-chlorophenylacetic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC with diode array detection; peak purity and threshold-based reporting per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) against calibration standards. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine generation in pyridine-free reagent; measures trace water based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and dilution; detection at sub-ppt levels. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode; endpoint detected by potential inflection due to AgCl precipitation. |
| Acid Value | Acid-Base Titration | Neutralization of carboxylic acid groups with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using sodium D-line light source in a temperature-controlled polarimeter; assesses chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal analysis via controlled heating of capillary-packed sample; identifies onset and range of solid-to-liquid transition. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to determine volume-based particle size distribution. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 750 C to remove organic matter, followed by weighing of inorganic residue to assess inorganic ash content. |
| Microbial Contamination | Membrane Filtration | Filtration of dissolved sample through sterile membrane, followed by incubation on appropriate agar media for aerobic microbial enumeration. |
Technical Specifications of alpha-Bromo-2-chlorophenylacetic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of alpha-Bromo-2-chlorophenylacetic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of alpha-Bromo-2-chlorophenylacetic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of alpha-Bromo-2-chlorophenylacetic acid
Industrial alpha-Bromo-2-chlorophenylacetic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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