China Factory Direct
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| CAS number | 141642-82-2 |
| Product name | ETHYL 1-BOC-5-OXO-HEXAHYDRO-1H-AZEPINE-4-CARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate | Used to construct nitrogen-containing heterocyclic drug molecules; serves as a key intermediate in multistep syntheses |
| Chemical Research | Protecting group reagent | BOC (tert-butoxycarbonyl) protects amino groups to enable selective reactions in peptide synthesis or complex molecule synthesis |
| Pharmaceutical R&D | Synthesis of γ-aminobutyric acid (GABA) analogs | Serves as a precursor to the azepane ring system for preparing neuroactive drug candidates |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210-220 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification via retention time matching and threshold-based reporting per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., ethyl acetate, toluene, methanol) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, Ni, As) using inductively coupled plasma mass spectrometry with detection limits <1 ppm. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after anion exchange separation. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled high-temperature ashing (700-800 C) and weighing. |
| Optical Rotation | Polarimetry | Determination of specific rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting conditions. |
| pH of Solution | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous or aqueous-organic solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed sample using light scattering principles to determine volume-based particle size distribution. |
| Bulk Density | Tap Density Tester | Determination of mass per unit volume after standardized mechanical tapping per USP <616>. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Acid Value (mg KOH/g) | <=1.0 |
| Odor | Characteristic ester-like odor |
| Solubility | Soluble in common organic solvents (e.g., methanol, ethyl acetate, dichloromethane); insoluble in water |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.