2-(Boc-aminomethyl)-piperidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 141774-61-0 |
| Product name | 2-(Boc-aminomethyl)-piperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-(Boc-aminomethyl)-piperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-(Boc-aminomethyl)-piperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-(Boc-aminomethyl)-piperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Pharmaceutical Intermediates | Serves as a key building block in the synthesis of piperidine-containing drug molecules via condensation between amine and carboxylic acid functional groups. |
| Pharmaceutical Industry | Peptide Synthesis | Used as a non-natural amino acid derivative in solid-phase or solution-phase synthesis of peptides or peptidomimetics to introduce a piperidine side chain, thereby improving metabolic stability. |
| Chemical Industry | Protecting Reagent | Employs the tert-butoxycarbonyl (Boc) group to protect amine functionalities during organic synthesis, preventing undesired side reactions. |
| Biochemistry | Ligand Synthesis | Applied in the design and synthesis of nitrogen-based bidentate ligands for use in metal-catalyzed reaction systems. |
Manufacturing Quality Control of 2-(Boc-aminomethyl)-piperidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and reporting against ICH Q3B thresholds. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at 20-25 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantification of elemental impurities (e.g., Pb, Cd, Ni, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection after aqueous extraction. |
| Residual Palladium | ICP-OES | Determination of palladium residue from catalytic hydrogenation steps via inductively coupled plasma optical emission spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change under controlled heating rate, indicating crystallinity and identity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of solid sample against established reference standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using Mie theory scattering pattern from laser beam interaction. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode to assess acidic/basic impurities. |
Technical Specifications of 2-(Boc-aminomethyl)-piperidine
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference standard |
| Optical Rotation | +15.0 to +19.0° (c=1, in CHCl3) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-(Boc-aminomethyl)-piperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-(Boc-aminomethyl)-piperidine
Safety Information of 2-(Boc-aminomethyl)-piperidine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-(Boc-aminomethyl)-piperidine
Industrial 2-(Boc-aminomethyl)-piperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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