2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 141776-47-8 |
| Product name | 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antimicrobial drug intermediate for synthesizing novel broad-spectrum antibiotics (e.g., quinolone derivatives) | Used as a key structural building block in multi-step organic synthesis; active pharmaceutical ingredient (API) is typically prepared via sulfonamidation, cyclization, and purification processes |
Manufacturing Quality Control of 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with reference spectra to confirm the presence of characteristic functional groups (e.g., sulfonamide, imidazopyridine ring). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Utilize ¹H NMR to analyze chemical shifts, integration areas, and coupling constants of hydrogen atoms, verifying structural consistency. | |
| Mass Spectrometry (MS or HRMS) | Obtain molecular ion peaks and fragment information via electrospray ionization (ESI) or electron impact (EI), confirming molecular weight and elemental composition. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a specific mobile phase (e.g., methanol/water or acetonitrile/buffer salt) for gradient or isocratic elution, quantifying the main component using a UV detector (e.g., 254 nm). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Similar to content determination conditions, but optimize separation parameters to effectively resolve potential process impurities and degradation products. Quantify impurities using area normalization method or corrected factor method with the active ingredient as internal standard. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with polar or non-polar capillary columns and FID detection. Determine residual organic solvents (e.g., dichloromethane, methanol, DMF) from synthesis or purification processes according to ICH Q3C guidelines. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Drying Loss Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight, calculate the percentage of mass loss to assess moisture and volatile content. |
| Charring Residue / Ash Content | Charring Residue Test Method | Ignite the sample at high temperature (typically 700–800°C) until constant weight, measuring the amount of inorganic impurities to evaluate residual inorganic salts or metal catalysts. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After wet digestion of samples, determine levels of heavy metals such as lead, cadmium, mercury, and arsenic using AAS or inductively coupled plasma mass spectrometry (ICP-MS), ensuring compliance with pharmacopoeial limits. |
| pH Value (for solution formulations) | pH Meter Measurement | Prepare a solution of defined concentration and measure its acidity or alkalinity using a calibrated pH meter, reflecting the dissociation characteristics of the sulfonamide group. |
| Polymorphism (if applicable) | X-Ray Powder Diffraction (XRPD) | Compare XRPD patterns to confirm whether the drug substance is in the expected crystalline form, avoiding potential impacts on solubility or stability due to polymorphic differences. |
| Stability-Indicating Test | Forced Degradation Test + HPLC/MS Coupling | Subject samples to forced degradation under acidic, basic, oxidative, thermal, and photolytic conditions; combine HPLC and mass spectrometry analysis to identify degradation products and verify the stability-indicating capability of the analytical method. |
Technical Specifications of 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide
| Test Item | Specification |
|---|---|
| Appearance | White to gray to brown powder or crystals |
| Purity | >=98.5% (LC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 182–186°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide
Safety Information of 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide
Industrial 2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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