ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 141872-22-2 |
| Product name | ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediate for synthesizing antibacterial agents (e.g., fluoroquinolone derivatives) | Used to construct the quinolone core structure via amidation, cyclization, and other steps following chiral resolution or asymmetric synthesis |
| Pesticide R&D | Structural modification unit for novel insecticides and fungicides | Integrated as a heterocyclic building block into active molecules to enhance target binding affinity and metabolic stability |
| Organic Synthesis | Multifunctional synthon for high-value fine chemicals | Applied in transition-metal-catalyzed coupling, reductive amination, ester exchange, and other reactions to construct functional molecules containing a pyrazine scaffold |
Manufacturing Quality Control of ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using isotopic detection for high sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 500-600 C followed by weighing of inorganic residue after sulfuric acid treatment. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to obtain volume-weighted particle size distribution (D10, D50, D90). |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH measurement of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration and Culture | Enumeration of aerobic microorganisms and detection of specified pathogens per USP <61> and <62>. |
Technical Specifications of ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE
Safety Information of ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE
Industrial ETHYL 3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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