Methyl 2-oxoindole-6-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 14192-26-8 |
| Product name | Methyl 2-oxoindole-6-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 2-oxoindole-6-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 2-oxoindole-6-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 2-oxoindole-6-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate | Used in the synthesis of various drug molecules, including anticancer agents and cardiovascular therapeutics. |
| Chemical | Synthesis of other compounds | Serves as a raw material or intermediate in synthetic reactions for other organic compounds. |
| Biochemistry | Research tool | Applied in mechanistic studies of specific enzymes in biological systems and in drug screening. |
Manufacturing Quality Control of Methyl 2-oxoindole-6-carboxylate
| Test Item | Common Testing Methods | Method Description |
|---|---|---|
| Identification (Identity) | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) |
The structure of the compound (2-oxoindole-6-carboxylic acid methyl ester) is confirmed by comparing characteristic IR absorption peaks, ¹H NMR chemical shifts and coupling constants, or HPLC-MS retention time and mass-to-charge ratio (m/z) with reference standards. |
| Assay (Content Determination) | High-Performance Liquid Chromatography (HPLC) | A reversed-phase C18 column is used with methanol-water or acetonitrile-water as the mobile phase for isocratic or gradient elution. The main component content is calculated using an external standard method with a UV detector (typically at 254 nm or set according to maximum absorbance wavelength). |
| Related Substances/Impurity Check | High-Performance Liquid Chromatography (HPLC) | A high-resolution reversed-phase HPLC method is employed to separate the main peak from potential impurities (such as starting materials, intermediates, degradation products, etc.). Impurity limits are controlled using area normalization or corrected factor self-comparison methods. |
| Residual Solvents | Gas Chromatography (GC), Headspace Sampling (Headspace-GC) | Based on ICH Q3C guidelines, headspace-gas chromatography is used to detect residual organic solvents (e.g., methanol, dichloromethane, DMF) from the synthetic process, with quantification performed using an FID detector. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Drying under Atmospheric Pressure | The sample is dried at a specified temperature (e.g., 105°C) until constant weight is achieved, and the percentage of mass loss is measured to assess moisture and volatile components. |
| Melting Point | Capillary Melting Point Method or Differential Scanning Calorimetry (DSC) | The phase transition temperature range from solid to liquid is measured, serving as an auxiliary indicator of purity and crystalline form. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric Karl Fischer titration is used to accurately determine trace water content in the sample. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Elemental impurities such as lead, cadmium, mercury, and arsenic are tested according to pharmacopoeia general chapters to ensure compliance with safety limits. |
Technical Specifications of Methyl 2-oxoindole-6-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 2-oxoindole-6-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 2-oxoindole-6-carboxylate
Safety Information of Methyl 2-oxoindole-6-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 2-oxoindole-6-carboxylate
Industrial Methyl 2-oxoindole-6-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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