Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 141942-85-0 |
| Product name | Ethyl (R)-(-)-4-cyano-3-hydroxybutyate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral synthetic intermediate for the preparation of drugs treating cardiovascular diseases, diabetes, and other conditions | Prepared via asymmetric catalytic hydrogenation or other chiral synthesis methods to yield R(−)-ethyl 4-cyano-3-hydroxybutyrate, followed by subsequent chemical transformations to generate the target drug molecule |
| Chemical Research | Employed as a key chiral building block in organic synthesis | Participates in various organic reactions—including esterification, amidation, and coupling reactions with other compounds—to construct complex chiral molecular frameworks |
| Pesticides | Serves as a synthetic precursor for certain high-efficacy, low-toxicity pesticides | Converted into biologically active pesticide ingredients through specific chemical modification steps |
Manufacturing Quality Control of Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~210 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation on a chiral stationary phase (e.g., Chiralpak AD-H) with UV detection; ee calculated from peak area ratio of R- and S-enantiomers. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection, quantifying common solvents (e.g., ethanol, ethyl acetate, toluene) against internal standard calibration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent; water reacts stoichiometrically with iodine in pyridine/methanol medium. |
| Heavy Metals (as Pb) | ICP-MS | Quantitative determination of trace metals (e.g., Pb, Cd, Ni, Cu) after acid digestion, using isotopic detection with high sensitivity and multi-element capability. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of anions on an ion-exchange column with suppressed conductivity detection; chloride quantified via external calibration. |
| Related Substances | HPLC-UV (Forced Degradation) | Stress testing (acid/base/oxidative/thermal/light) followed by HPLC-UV analysis to identify and quantify degradants and synthetic impurities. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Comparison of sample solution (in specified solvent) against platinum-cobalt standards under controlled lighting conditions. |
| Specific Optical Rotation | [α]D | Measurement of rotation angle of plane-polarized light at 589 nm using a digital polarimeter; reported as degrees per dm·g/mL. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700–800 °C to ash organic matter; residue mass measured after cooling in desiccator. |
| Acid Value | Acid-Base Titration | Titration with standardized KOH solution in alcoholic medium using phenolphthalein indicator; measures free carboxylic acid impurities. |
| Ethyl Ester Content | 1H NMR Spectroscopy | Quantitative integration of diagnostic proton signals (e.g., CH₃CH₂O– quartet vs. backbone protons) relative to an internal standard (e.g., 1,3,5-trimethoxybenzene). |
Technical Specifications of Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -37.0 to -31.0 deg (c=1, in CHCl3) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.445–1.455 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
Safety Information of Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
Industrial Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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