China Factory Direct
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| CAS number | 14205-39-1 |
| Product name | Methyl 3-aminocrotonate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for dihydropyridine calcium channel blockers (e.g., nifedipine, nitrendipine, nimodipine) | Participates in the Hantzsch dihydropyridine synthesis with o-nitrobenzaldehyde and β-keto esters |
| Pharmaceuticals | Intermediate for vitamin B6 (pyridoxol) and pyridoxal phosphate inhibitors | Serves as a C4 building block in the construction of pyridine rings or thiazole derivatives |
| Agrochemicals | Intermediate for neonicotinoid insecticides (e.g., imidacloprid, thiacloprid) | Acts as an amine source in condensation reactions forming the neonicotinoid core or related heterocyclic compounds |
| Chemicals/Materials | Aminomethylation reagent or Michael addition reagent in organic synthesis | Used to prepare nitrogen-containing heterocyclic derivatives such as dihydropyridones, pyridones, and pyrroles |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210-230 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and peak area normalization. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify methanol, ethyl acetate, and other process solvents per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and dilution. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator to determine free carboxylic acid equivalents. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital melting point instrument. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 20 deg C using sodium D-line (589 nm) to assess chiral purity. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue after high-temperature ashing (700-800 deg C) to estimate inorganic ash content. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser diffraction to determine D10, D50, D90 values per ISO 13320. |
| Test Item | Specification |
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| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 65–69°C |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic ester-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.