4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1421312-34-6 |
| Product name | 4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1421312-34-6
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1421312-34-6 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1421312-34-6
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a pharmaceutical intermediate for synthesizing biologically active isoquinoline compounds | Organic synthesis reactions, including esterification, substitution, and coupling |
| Pharmaceutical Chemicals | Serves as a structural building block for anti-inflammatory or anticancer candidate drugs | Multi-step synthesis involving protecting group strategies and high-efficiency catalysts |
| Biochemical Research | Used as a precursor for fluorescent probes or molecular labels | Optically active modification and functional grafting processes |
| Materials Science | Employed as a building block in the development of novel optoelectronic materials | High-temperature condensation and copolymerization techniques |
Manufacturing Quality Control of 1421312-34-6
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, condition, and presence of visible foreign matter under natural light or standard light source. |
| Identification | Fourier Transform Infrared Spectroscopy (FTIR) | Compare the sample with a standard spectrum to confirm functional groups in the molecular structure (e.g., hydroxyl, ester, aromatic rings) based on characteristic absorption peaks. |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹³C-NMR) | Analyze chemical shifts, coupling constants, and integration areas in hydrogen and carbon spectra to confirm the compound's structure. | |
| Mass Spectrometry (MS or HRMS) | Determine the molecular ion peak to confirm molecular weight and fragment ions, verifying the molecular formula of the target compound. | |
| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with a UV detector (typically at 254 nm or 280 nm), and determine the content of the main component using external standard or normalization methods. |
| Impurity Analysis | HPLC-DAD or LC-MS | Identify and quantify related substances (e.g., synthetic intermediates, degradation products) by combining retention time with spectral or mass spectrometric information. |
| Moisture Content | Karl Fischer Titration | Accurately measure moisture content using volumetric or coulometric methods, suitable for trace water detection. |
| Residual Solvents | Gas Chromatography (GC) | Use an appropriate chromatographic column (e.g., DB-624) to detect organic solvents potentially remaining from the production process (e.g., methanol, ethanol, dichloromethane). |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detect residual amounts of toxic elements such as lead, cadmium, mercury, and arsenic to meet pharmacopoeia limits. |
| Melting Point | Capillary Melting Point Method | Determine the initial and final melting temperatures using a melting point apparatus to preliminarily assess purity and consistency. |
| Solubility | Dissolution Test | Test solubility in different solvents (e.g., water, ethanol, DMSO, methanol) to evaluate formulation applicability. |
| Polymorphism Analysis (if applicable) | X-ray Powder Diffraction (XRD) | Analyze characteristic diffraction peaks to identify polymorphic forms and ensure batch-to-batch consistency. |
| Thermal Stability | Differential Scanning Calorimetry (DSC) | Determine melting, decomposition, or phase transition temperatures to assess thermal behavior and stability. |
| Uniformity of Content/Dissolution (for formulations) | HPLC Method | If this compound is an active pharmaceutical ingredient, uniformity of content and dissolution tests must be performed in formulations to ensure quality control. |
Technical Specifications of 1421312-34-6
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1421312-34-6
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1421312-34-6
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Industrial 1421312-34-6 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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