Protionamide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 14222-60-7 |
| Product name | Protionamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Protionamide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Protionamide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Protionamide
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antitubercular agent | Used as a second-line antitubercular drug in combination therapy for isoniazid-resistant pulmonary tuberculosis and non-resistant tuberculosis, typically co-administered with rifampicin, pyrazinamide, and ethambutol; exerts antibacterial activity by inhibiting mycobacterial cell wall synthesis |
Manufacturing Quality Control of Protionamide
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Compare characteristic absorption peaks of the sample and reference standard under identical conditions to confirm consistency of chemical structure. |
| High-Performance Liquid Chromatography (HPLC) | Verify consistency between sample and reference standard by comparing retention times; used as supportive identification. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Quantify the main component using a reversed-phase column (e.g., C18), UV detector (around 254 nm), and external or internal standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate impurities using gradient or isocratic elution to detect degradation products or synthesis intermediates; calculate individual impurity levels and total impurity content. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing (e.g., methanol, ethanol, dichloromethane) in accordance with ICH guidelines. |
| Water Content | Karl Fischer Titration | Accurately determine moisture content in the active pharmaceutical ingredient (API) to ensure compliance with pharmacopoeial limits. |
| Crystal Form Analysis | X-Ray Powder Diffraction (XRPD) | Analyze characteristic peaks of crystal structure to confirm the crystal form meets specifications; used for polymorphic control. |
| Particle Size Distribution | Laser Particle Size Analysis | Measure particle size distribution of the API, which affects solubility and performance in formulation processes. |
| Melting Point | Capillary Melting Point Determination | Determine the melting temperature range using a melting point apparatus; serves as a physical identification parameter and purity indicator. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detect levels of harmful elements such as lead, cadmium, mercury, and arsenic to comply with pharmacopoeial requirements or ICH Q3D elemental impurity limits. |
| Sulfated Ash / Residue on Ignition | Residue on Ignition Test | Weigh residue after high-temperature ignition of the sample to assess total inorganic impurities. |
| Loss on Drying | Thermogravimetric Analysis or Oven Method | Dry the sample at a specified temperature for a defined period and measure weight loss, reflecting the loss of volatile components (including moisture). |
Technical Specifications of Protionamide
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 134–138°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Protionamide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Protionamide
Packaging of Protionamide
Industrial Protionamide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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