1-N-Boc-3-Azetidinecarboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 142253-55-2 |
| Product name | 1-N-Boc-3-Azetidinecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-N-Boc-3-Azetidinecarboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-N-Boc-3-Azetidinecarboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-N-Boc-3-Azetidinecarboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Serves as a synthetic intermediate for preparing nitrogen-containing heterocyclic drug molecules, such as antiviral or anticancer candidate compounds | Participates in multistep organic synthesis via Boc deprotection, carboxyl activation, or functional group modification on the ring |
| Medicinal Chemistry | Constructs β-amino acid building blocks for designing peptide mimetics or protease inhibitors | Undergoes amide bond formation with amines or amino acids using solid-phase or solution-phase peptide synthesis techniques |
| Organic Synthesis | Acts as a chiral building block in asymmetric synthesis reactions to construct complex heterocyclic systems | Enables stereoselective reactions—such as alkylation and Michael addition—via induction by the chiral center |
| Biochemical Research | Used to synthesize probe molecules or labeled ligands for studying biomolecular target interactions | Carboxyl coupling with fluorophores or biotin enables applications in affinity chromatography or cellular imaging |
Manufacturing Quality Control of 1-N-Boc-3-Azetidinecarboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification by retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, DMF, ethyl acetate) via headspace GC with flame ionization detection using calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange column separation. |
| Residual Boc Protecting Group | HPLC-UV | Monitors incomplete deprotection or residual Boc-anhydride derivatives by specific HPLC-UV method with optimized mobile phase. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles against established reference standards under controlled lighting. |
| pH of Aqueous Solution | pH Meter | Measures hydrogen ion activity in a 1% w/v aqueous suspension using calibrated pH electrode per EP 2.2.3. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after drying at 60 C under vacuum for 2 hours. |
Technical Specifications of 1-N-Boc-3-Azetidinecarboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 82-86°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | +15.0 to +19.0° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-N-Boc-3-Azetidinecarboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-N-Boc-3-Azetidinecarboxylic acid
Safety Information of 1-N-Boc-3-Azetidinecarboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-N-Boc-3-Azetidinecarboxylic acid
Industrial 1-N-Boc-3-Azetidinecarboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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