6-FLUORONICOTINIC ACID METHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1427-06-1 |
| Product name | 6-FLUORONICOTINIC ACID METHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-FLUORONICOTINIC ACID METHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-FLUORONICOTINIC ACID METHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-FLUORONICOTINIC ACID METHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing fluorinated pyridine-based insecticides and fungicides | Produced via esterification of 6-fluoronicotinic acid with methanol under acidic conditions; used in subsequent construction of the active pyridine ring structure |
| Pharmaceuticals | Intermediate for synthesizing antiviral agents, kinase inhibitors, and other drug molecules | Serves as a fluorinated heterocyclic building block in nucleophilic substitution and coupling reactions (e.g., Suzuki, Buchwald–Hartwig) to construct drug scaffolds |
| Chemical Reagents | Standard reference material or reaction intermediate for organic synthesis | Used as a high-purity raw material in laboratory-scale organic synthesis and structural modification studies |
Manufacturing Quality Control of 6-FLUORONICOTINIC ACID METHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase C18 column and calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., starting materials, intermediates, degradants) via gradient elution and peak area comparison. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, dichloromethane) using flame ionization detection with headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Acid Value | Acid-Base Titration | Measures free carboxylic acid groups via titration with standardized NaOH solution using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Identifies purity and identity by observing temperature range at which solid transitions to liquid under controlled heating. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity and identity by detecting rotation of plane-polarized light in solution at specified concentration and wavelength. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine size distribution based on light scattering pattern. |
| Bulk Density | USP <616> Method | Determines mass per unit volume of powder under standardized tapping conditions using calibrated cylinder and balance. |
Technical Specifications of 6-FLUORONICOTINIC ACID METHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-FLUORONICOTINIC ACID METHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-FLUORONICOTINIC ACID METHYL ESTER
Safety Information of 6-FLUORONICOTINIC ACID METHYL ESTER
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 6-FLUORONICOTINIC ACID METHYL ESTER
Industrial 6-FLUORONICOTINIC ACID METHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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