2-[(tert-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 142847-18-5 |
| Product name | 2-[(tert-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 142847-18-5
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 142847-18-5 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 142847-18-5
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate in the synthesis of peptide-based therapeutics, used to construct bioactive peptides containing tyrosine residues | Protected amino acid monomer in solid-phase peptide synthesis (SPPS); the Boc group protects the α-amino functionality to prevent side reactions |
| Biochemical Research | Preparation of labeled or modified tyrosine derivatives for studying protein structure and function | Participates in enzymatic or chemical conjugation reactions after deprotection to introduce fluorescent tags, biotin, or other functional groups |
| Peptide Synthesis | Building block in standard Fmoc/BOC strategies for automated or manual peptide chain elongation | BOC protecting group removed under acidic conditions (e.g., trifluoroacetic acid), followed by subsequent coupling reaction |
Manufacturing Quality Control of 142847-18-5
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies BOC-DL-Tyrosine by reversed-phase HPLC with UV detection at 210-220 nm, using a calibrated standard reference material. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., deprotected tyrosine, BOC-anhydride, di-BOC derivatives) via gradient HPLC separation and UV response. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., dichloromethane, ethyl acetate, methanol) using gas chromatography with flame ionization detection against certified standards. |
| Water Content | Karl Fischer Titration | Determines water content volumetrically or coulometrically by iodine-based redox titration in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-MS | Quantifies trace metals (Pb, Cd, Hg, As, Cr, Ni) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Sulfate Content | Ion Chromatography | Separates and quantifies sulfate ions using suppressed conductivity detection following sample dissolution and dilution. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by ignition at 700-800 C and weighing the residual residue after cooling in a desiccator. |
| Optical Rotation | Polarimetry | Measures specific optical rotation using sodium D-line light to confirm chiral integrity and absence of significant racemization. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using Mie scattering theory and calibrated instrument optics. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a 1% w/v aqueous suspension using a calibrated glass electrode pH meter. |
Technical Specifications of 142847-18-5
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 195–199°C |
| Optical Rotation | -5.0° to +5.0° (c=1, in 1N HCl) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 142847-18-5
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 142847-18-5
Industrial 142847-18-5 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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