China Factory Direct
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| CAS number | 14316-06-4 |
| Product name | D-Alanine Methyl Ester Hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for synthesizing antibiotics (e.g., β-lactams) | Used as a chiral building block in peptide coupling or esterification reactions to prepare biologically active amino acid derivatives |
| Chemical Synthesis | Synthesis of non-natural amino acids and chiral ligands | Applied as a chiral source in acylation, reduction, or condensation reactions to introduce methyl ester and amino functionalities |
| Pesticides | Synthesis of chiral pesticide intermediates | Employed to construct alanine-containing insecticidal or fungicidal molecules, enhancing biological selectivity |
| Research Reagents | Biochemical and drug screening research | Utilized as a reference standard or precursor in enzyme activity assays, chiral recognition experiments, and structure–activity relationship studies |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Alanine Methyl Ester Hydrochloride) | Acid-Base Titration with NaOH | Quantifies active compound by neutralizing HCl salt with standardized NaOH using potentiometric or visual endpoint detection. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC | Separates D- and L-enantiomers on a chiral stationary phase; quantifies D-isomer purity via peak area ratio. |
| Water Content | Karl Fischer Titration | Measures water by coulometric or volumetric reaction of iodine with water in anhydrous methanol-based medium. |
| Residual Solvents (Methanol, Ethyl Acetate) | Gas Chromatography (GC-FID) | Separates and quantifies volatile solvents using capillary column and flame ionization detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Detects trace metal impurities after acid digestion by measuring elemental mass-to-charge ratios with high sensitivity. |
| Chloride Content | Potentiometric Titration with AgNO3 | Determines chloride ions by titration with silver nitrate using silver indicator electrode. |
| pH (1% aqueous solution) | pH Meter Measurement | Measures hydrogen ion activity in aqueous solution using calibrated glass electrode. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled lighting and against standard references. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity. |
| Related Substances (Impurity Profile) | Reverse-Phase HPLC-UV | Separates and detects structurally related impurities (e.g., D-alanine, methyl ester hydrolysis products) using C18 column and UV detection. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing of residual residue. |
| Microbial Contamination | Membrane Filtration and Plate Count | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148-152°C |
| Optical Rotation | -6.0 to -9.0° (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.