H-D-CHG-OME HCL Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 14328-64-4 |
| Product name | H-D-CHG-OME HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for H-D-CHG-OME HCL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk H-D-CHG-OME HCL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of H-D-CHG-OME HCL
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral building block for synthesizing novel antimicrobial agents (e.g., cyclic peptide antibiotics) | Used as a chiral auxiliary in peptide coupling reactions to introduce the D-cyclohexylglycine moiety during solid-phase or solution-phase peptide synthesis |
| Pharmaceutical Intermediates | Linker module for targeted protein degradation chimeras (PROTACs) | Integrated into the linker region between the E3 ligase ligand and the target protein ligand via ester hydrolysis, amination, and coupling reactions |
| Organic Synthesis | Precursor for chiral resolving agents and asymmetric catalytic auxiliaries | After base-catalyzed ester hydrolysis and amine protection/derivatization, used to prepare chiral phase-transfer catalysts or asymmetric hydrogenation ligands |
Manufacturing Quality Control of H-D-CHG-OME HCL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, dichloromethane) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, with detection at sub-ppt levels. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential inflection corresponding to AgCl precipitation. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid-to-liquid phase transition occurs, indicating crystallinity and absence of eutectic impurities. |
| pH (1% w/v aqueous solution) | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous suspension to assess acid salt behavior and hydrolytic stability. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 700-800 C to constant weight; residual inorganic ash quantified by mass difference to assess inorganic impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering principles to determine D10, D50, D90 values relevant to filtration and dissolution performance. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic bacteria and fungi via filtration, membrane transfer to culture media, and colony counting per USP <61>. |
Technical Specifications of H-D-CHG-OME HCL
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142°C to 146°C |
| Optical Rotation | -22° to -18° (c=1, in H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of H-D-CHG-OME HCL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of H-D-CHG-OME HCL
Packaging of H-D-CHG-OME HCL
Industrial H-D-CHG-OME HCL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply