(R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 143322-57-0 |
| Product name | (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Serves as a chiral drug intermediate for synthesizing 5-HT receptor modulators or candidate compounds for antidepressant/antipsychotic agents | Produced via asymmetric synthesis or chiral resolution; commonly involved in key steps such as palladium-catalyzed coupling or reductive amination to construct the target molecular scaffold |
Manufacturing Quality Control of (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible foreign particles under natural light or standard illumination. |
| Identification (Structural Confirmation) | Nuclear Magnetic Resonance Spectroscopy (NMR) | Utilize ¹H-NMR and ¹³C-NMR to analyze hydrogen and carbon frameworks, confirming that the molecular structure matches the target compound. |
| Mass Spectrometry (MS) | Determine molecular ion peaks using high-resolution mass spectrometry (HRMS) to confirm molecular formula and exact molecular weight. | |
| Infrared Spectroscopy (IR) | Measure characteristic functional group absorption peaks and compare with reference spectra to confirm chemical structure. | |
| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Use reverse-phase HPLC (e.g., C18 column) with UV detection to determine the content of the main component and related substances, calculating purity. |
| Related Substances (Impurity Profiling) | HPLC-UV or UPLC-MS | Separate and detect organic impurities such as starting materials, intermediates, and degradation products from synthesis processes; typically using gradient elution. |
| Chiral Purity (Enantiomeric Excess) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use chiral stationary phase columns to separate enantiomers, assessing the enantiomeric purity of the (R)-configuration and ensuring no contamination by the (S)-isomer. |
| Residual Solvents | Gas Chromatography (GC) | Test for residual volatile organic solvents (e.g., methanol, ethanol, dichloromethane) used during production according to ICH guidelines. |
| Drying Loss (LOD) | Thermogravimetric Analysis (TGA) or Oven Method | Heat the sample at a specified temperature for a set duration and measure mass loss to assess moisture and volatile component content. |
| Moisture Content | Karl Fischer Titration | Accurately determine the content of bound and free water in the sample; suitable for moisture-sensitive compounds. |
| Melting Point | Melting Point Instrument Method | Determine the melting temperature range using capillary tube method or automated melting point instrument for preliminary identification and purity assessment. |
| Polymorphic Analysis (if applicable) | X-Ray Powder Diffraction (XRPD) | Analyze the crystalline structure of solid samples to confirm the presence or absence of polymorphism, ensuring batch-to-batch consistency. |
| Particle Size Distribution (if applicable for solid dosage form precursors) | Laser Diffraction (LDL) | Measure particle size distribution of active pharmaceutical ingredients, which affects dissolution behavior and subsequent formulation processes. |
Technical Specifications of (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148°C to 152°C |
| Optical Rotation | +22.5° to +24.5° (c=1, in methanol) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole
Safety Information of (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole
| Pictograms |    |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole
Industrial (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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