3,4,5-Trifluorophenylboronic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 143418-49-9 |
| Product name | 3,4,5-Trifluorophenylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3,4,5-Trifluorophenylboronic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3,4,5-Trifluorophenylboronic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3,4,5-Trifluorophenylboronic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used in the synthesis of various drug molecules | Serves as a key intermediate or starting material in drug molecule construction, primarily via Suzuki cross-coupling and related reactions |
| Agrochemicals | Active ingredient or precursor in agrochemical formulations | Incorporated into target compound structures via cross-coupling reactions to enhance biological activity or stability |
| Materials Science | Development of novel functional materials | Employed in organic synthesis—particularly metal-catalyzed coupling reactions—to prepare functional polymers or other materials with specialized properties (e.g., corrosion resistance, low surface energy) |
| Fine Chemicals | Production of high-performance chemicals | Reacted with other reagents under controlled conditions to yield specialty chemicals for applications in electronics, coatings, and related industries |
Manufacturing Quality Control of 3,4,5-Trifluorophenylboronic acid
| Test Item | Common Testing Method | Method Summary |
|---|---|---|
| Purity (Active Ingredient Content) | High-Performance Liquid Chromatography (HPLC) | Using a C18 reversed-phase column with water-acetonitrile or methanol as the mobile phase, and UV detection at 254 nm. The content of the main component is quantified by external or internal standard method to assess purity. |
| Impurity Profile (Organic Impurities) | HPLC-UV / HPLC-MS | After HPLC separation, impurities such as process-related impurities and degradation products (e.g., borate esters, unreacted starting materials, dimers) are identified and quantified using UV or mass spectrometric detection. MS is used for structural confirmation. |
| Water Content | Karl Fischer Titration | Quantitative reaction between water and an iodine-sulfur dioxide-pyridine-methanol system; trace moisture in the sample is determined by potentiometric or coulometric methods, compliant with pharmacopeial requirements (e.g., USP/EP). |
| Melting Point | Melting Point Apparatus | The melting temperature range of the sample is measured using a digital melting point apparatus (literature value approximately 120–125°C), used for preliminary identification and purity assessment—impurities typically lower the melting point or broaden its range. |
| Fluorine Content | Ion Chromatography (IC) or Fluoride Ion-Selective Electrode | After alkali fusion or hydrolysis, fluoride ion concentration is determined by ion chromatography; alternatively, fluoride ion-selective electrode potentiometry is used to verify the theoretical content of three fluorine atoms in the molecule. |
| Boron Content | Colorimetric Method with Azomethine-H Acid or ICP-OES | In acidic conditions, boron reacts with azomethine-H acid to form a colored complex, and absorbance is measured at 530 nm; alternatively, boron content is directly determined using Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES). |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection GC with FID detection is used to determine residual organic solvents (e.g., methanol, ethanol, DMF, THF), in compliance with ICH Q3C guidelines. |
| Appearance and Color | Visual Inspection + Colorimetry | Observe physical state (white to off-white crystalline powder); colorimeter may be used to measure Lab* values if necessary, ensuring no significant discoloration or colored impurities. |
| pH Value (Aqueous Solution) | pH Meter | Prepare a 1% aqueous solution of the sample and measure pH using a calibrated pH meter. The expected value is near neutral (approximately 6–8), to evaluate abnormal acidity or alkalinity. |
| Particle Size Distribution (Powder Sample) | Laser Diffraction | Applicable for powdered active pharmaceutical ingredients; measures particle size distribution to ensure process consistency and to assess impact on solubility and formulation performance. |
Technical Specifications of 3,4,5-Trifluorophenylboronic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3,4,5-Trifluorophenylboronic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3,4,5-Trifluorophenylboronic acid
Safety Information of 3,4,5-Trifluorophenylboronic acid
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 3,4,5-Trifluorophenylboronic acid
Industrial 3,4,5-Trifluorophenylboronic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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