China Factory Direct
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| CAS number | 1435-43-4 |
| Product name | 3,5-Difluorochlorobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing novel fluorinated insecticides (e.g., flupyradifurone) | Constructs the target molecular scaffold via multi-step reactions including nitration, reduction, diazotization, and fluorination |
| Pharmaceuticals | Fluorinated aromatic ring building block for anticancer agents (e.g., BTK inhibitors) and anti-inflammatory drugs | Serves as a starting material for aromatic ring fluorination, introducing the fluorinated moiety into drug molecules via lithiation–electrophilic substitution or cross-coupling reactions |
| Materials | Monomer for high-temperature- and corrosion-resistant fluorinated liquid crystals and specialty engineering plastics | Integrated into liquid crystal core structures or polymer backbones via nucleophilic substitution or metal-catalyzed coupling reactions |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies 3,5-difluorochlorobenzene by retention time and peak area against a calibrated standard. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration based on iodine consumption in a pyridine-methanol solvent system. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic impurities by weighing residue after high-temperature ashing. |
| Chloride Impurities | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Heavy Metals | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Detects trace metals (e.g., Pb, Cd, Hg) by atomic emission following acid digestion. |
| Acid-Consuming Substances | Acid-Base Titration | Measures acidic impurities by titration with standardized NaOH solution using phenolphthalein indicator. |
| Non-Volatile Residue | Evaporation and Gravimetry | Quantifies residue left after controlled evaporation of a known sample mass under specified conditions. |
| Color | Visual Comparison or Spectrophotometry (APHA/Pt-Co scale) | Evaluates color intensity by comparing sample to platinum-cobalt standard solutions or measuring absorbance at 455 nm. |
| Density | Digital Density Meter | Determines density from oscillation period of a U-tube filled with sample at controlled temperature. |
| Refractive Index | Refractometry | Measures refractive index using total internal reflection principle at specified wavelength (e.g., 589 nm) and temperature. |
| Boiling Range | Distillation (Micro or ASTM D1078) | Determines boiling point distribution by controlled distillation and temperature monitoring. |
| Organic Volatile Impurities | Headspace Gas Chromatography-Mass Spectrometry (HS-GC-MS) | Identifies and quantifies residual solvents and volatile impurities using thermal headspace injection and mass spectral detection. |
| Test Item | Specification |
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| Appearance | Pale-yellow liquid |
| Purity | >=98.5% (GC) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Refractive Index (n20/D) | 1.495–1.505 |
| Relative Density (20°C/25°C) | 1.31–1.33 g/cm³ |
| Odor | Characteristic aromatic odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.