1-Phenylcyclobutanecarbonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 14377-68-5 |
| Product name | 1-Phenylcyclobutanecarbonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Phenylcyclobutanecarbonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Phenylcyclobutanecarbonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Phenylcyclobutanecarbonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key structural building blocks for synthesizing active pharmaceutical ingredients (APIs), including antidepressants and analgesics | Used as cyclobutylphenyl nitrile compounds in coupling reactions (e.g., Suzuki, Heck) or in cyanide hydrolysis/reduction to construct carboxylic acid or amine functional groups |
| Organic Synthesis | Building novel functional molecules containing a cyclobutane scaffold for drug discovery and materials science research | Applied in nucleophilic addition, cyclization, and metal-catalyzed nitrile transformations to introduce heterocyclic or fused-ring systems |
| Pesticide Development | Potential structural motif for insecticidal or fungicidal lead compounds | Employed as a rigid hydrophobic moiety to modify active molecules, optimizing lipophilicity, metabolic stability, and target binding affinity |
Manufacturing Quality Control of 1-Phenylcyclobutanecarbonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a calibrated column and carrier gas. |
| Related Substances | Gas Chromatography-Mass Spectrometry (GC-MS) | Separation followed by mass spectral identification and semi-quantitative assessment of impurities relative to main peak. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Sample heated to 700-800 C in a platinum crucible; residue weight measured after cooling in desiccator. |
| Heavy Metals | ICP-OES (Inductively Coupled Plasma Optical Emission Spectrometry) | Atomization and excitation of metals in high-temperature plasma; elemental quantification via characteristic emission wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Anion separation on ion-exchange column; chloride quantified by conductivity response relative to calibration standards. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile solvents partitioned into headspace above sample, injected and separated on capillary column with FID detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually as solid-to-liquid phase change under controlled heating rate per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of angle of rotation of plane-polarized light passing through solution; indicates chiral purity if applicable. |
| Appearance | Visual Inspection (in glass vial under controlled lighting) | Assessment of physical state, color, and clarity against defined standards (e.g., APHA color scale, clear and colorless). |
| Acid Value | Acid-Base Titration (NaOH standard solution) | Neutralization of acidic impurities with standardized sodium hydroxide; endpoint detected potentiometrically or with phenolphthalein. |
| Bulk Density | Tap Density Measurement (ASTM D1895) | Mass per unit volume determined after mechanical tapping of sample in graduated cylinder per standardized procedure. |
Technical Specifications of 1-Phenylcyclobutanecarbonitrile
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.525 - 1.535 |
| Relative Density (20°C/25°C) | 1.02 - 1.04 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Phenylcyclobutanecarbonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Phenylcyclobutanecarbonitrile
Safety Information of 1-Phenylcyclobutanecarbonitrile
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-Phenylcyclobutanecarbonitrile
Industrial 1-Phenylcyclobutanecarbonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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