4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 143782-23-4 |
| Product name | 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Serves as a key intermediate in the synthesis of JNK (c-Jun N-terminal Kinase) inhibitors, such as SP600125 | Organic synthesis (nucleophilic addition/cyclization) |
| Biochemical Research | Used to construct biologically active thiazole, imidazole, or thiadiazole derivatives | Heterocyclic compound synthesis |
| Drug Discovery | Applied in the design and screening of anti-inflammatory, antitumor, or neuroprotective drug candidates | Target-based medicinal chemistry synthesis |
Manufacturing Quality Control of 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) Nuclear Magnetic Resonance Hydrogen Spectrum (¹H NMR) Mass Spectrometry (MS) |
Confirm the structural characteristics of the target compound through characteristic absorption peaks in infrared spectroscopy, chemical shifts and coupling constants in nuclear magnetic resonance hydrogen spectrum, and molecular ion peaks and fragment ions in mass spectrometry. Compare with standard spectra or literature data for identification. |
| Content Determination | HPLC (High-Performance Liquid Chromatography) GC (Gas Chromatography, if applicable) |
Use reverse-phase HPLC (e.g., C18 column) with a UV detector (typically at 220–260 nm wavelength) for detection. Quantify using external standard method or internal standard method. If the compound has sufficient volatility and thermal stability, GC may also be used for content analysis. |
| Related Substances (Impurity) Check | HPLC (High-Performance Liquid Chromatography) | Use gradient elution or isocratic HPLC methods to separate the main component from potential process impurities and degradation products. Calculate the content of each impurity using area normalization or correction factor method, and control the total impurity and individual impurity limits. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH Q3C guidelines, use headspace injection or direct injection gas chromatography to detect residual organic solvents (such as dichloromethane, toluene, ethanol, etc.) from synthesis or purification processes. Use FID detector for quantification. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Conventional Drying Loss Method |
Dry the sample to constant weight under specified temperature (e.g., 105°C), measure the mass loss, and assess the water and volatile component content. |
| Melting Point | Capillary Melting Point Determination | Determine the initial and final melting temperatures of the sample using a melting point apparatus. Compare with literature values as an auxiliary indicator of purity and identity. |
| Moisture | Karl Fischer Titration | Accurately determine the moisture content in the sample using Karl Fischer titration (volumetric or coulometric method). Suitable for organic compounds sensitive to moisture. |
Technical Specifications of 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile
| Test Item | Specification |
|---|---|
| Appearance | White to yellow to green powder to lump |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile
Safety Information of 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile
Industrial 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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