(R)-1-Boc-3-Hydroxypiperidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 143900-43-0 |
| Product name | (R)-1-Boc-3-Hydroxypiperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-1-Boc-3-Hydroxypiperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-1-Boc-3-Hydroxypiperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-1-Boc-3-Hydroxypiperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for synthesizing chiral drugs | Target compounds are obtained via asymmetric synthesis or chiral resolution for antiviral, anticancer, and other drug manufacturing |
| Cosmetics | Development of biologically active cosmetic ingredients | Combined with other active substances to formulate products with antioxidant, moisturizing, and related functionalities |
| Pesticides | Synthetic raw material for certain high-efficacy, low-toxicity pesticides | Chemically modified and incorporated into pesticide molecular structures to enhance selectivity and environmental compatibility |
| Fine Chemicals | Important chiral auxiliary in organic synthesis | Participates in reactions under specific conditions to improve product enantiomeric purity |
| Materials Science | Enabling construction of novel chiral materials | Integrated with other materials to leverage its unique stereochemistry for functional polymer synthesis |
Manufacturing Quality Control of (R)-1-Boc-3-Hydroxypiperidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-220 nm, comparing peak area to calibrated standard. |
| Chiral Purity | Chiral HPLC | Separates (R)- and (S)-enantiomers on a chiral stationary phase and quantifies enantiomeric excess via peak area ratio. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., THF, EtOAc, MeOH) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric titration with iodine-based reagent reacting stoichiometrically with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Boc Reagent | GC-MS | Identifies and quantifies residual di-tert-butyl dicarbonate by gas chromatography coupled with mass spectrometric detection. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., de-Boc product, epimer, dimer) using gradient HPLC-UV. |
| Optical Rotation | [a]D Measurement | Determines specific optical rotation at 589 nm using a polarimeter to confirm chiral integrity and batch consistency. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a standardized aqueous suspension or solution using calibrated pH electrode. |
| Residue on Ignition | Gravimetric Analysis | Quantifies inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine size distribution based on angular scattering intensity of laser light. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtering sample through sterile membrane, then culturing on tryptic soy agar under controlled conditions. |
Technical Specifications of (R)-1-Boc-3-Hydroxypiperidine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | -23.0 to -20.0 deg (c=1, in methanol) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 72 to 76 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-1-Boc-3-Hydroxypiperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-1-Boc-3-Hydroxypiperidine
Packaging of (R)-1-Boc-3-Hydroxypiperidine
Industrial (R)-1-Boc-3-Hydroxypiperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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