(S)-1-Boc-3-hydroxypiperidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 143900-44-1 |
| Product name | (S)-1-Boc-3-hydroxypiperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-1-Boc-3-hydroxypiperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-1-Boc-3-hydroxypiperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-1-Boc-3-hydroxypiperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antipsychotic drugs such as paliperidone and risperidone | Chiral synthesis, amino protection |
| Pharmaceuticals | Used to construct drug molecules containing a piperidine scaffold | Esterification, reduction |
Manufacturing Quality Control of (S)-1-Boc-3-hydroxypiperidine
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white solid, crystalline powder) and visible impurities under natural light or standard illumination. |
| Purity (Chemical Purity) | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with UV detection (e.g., 210 nm or 220 nm). Determine the main component content and assess organic impurity levels using area normalization or external standard method. |
| Enantiomeric Purity (ee value) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Utilize chiral columns (e.g., Chiralpak AD-H, OD-H) to separate (S)- and (R)-enantiomers, and calculate enantiomeric excess (ee%). |
| Residual Solvents | Gas Chromatography (GC) | Following ICH Q3C guidelines, detect common solvent residues such as methanol, ethanol, dichloromethane, tetrahydrofuran, and ethyl acetate using FID detection. |
| Moisture Content | Karl Fischer Titration | Determine water content using either volumetric or coulometric Karl Fischer titration; suitable for moisture control in compounds containing hydroxyl groups. |
| Melting Point | Melting Point Instrument Method | Determine the melting range using an automatic melting point apparatus or capillary tube method, used for preliminary identification and purity assessment. |
| Structure Elucidation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H NMR and ¹³C NMR to analyze molecular structure and confirm chemical structure and stereochemistry of the target compound. |
| Structure Elucidation | Mass Spectrometry (MS) | Employ LC-MS or EI-MS to determine molecular ion peaks, verify molecular weight, and assist in structural identification. |
| Infrared Spectroscopy | Fourier Transform Infrared Spectroscopy (FT-IR) | Analyze characteristic functional group absorption peaks (e.g., C=O, O–H, C–O), used for auxiliary structural confirmation and batch-to-batch consistency checks. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detect heavy metal residues including lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopoeial limits (e.g., ChP, USP). |
| Residue on Ignition (Sulfated Ash) | Gravimetric Method | After high-temperature ignition, weigh the residual ash to assess inorganic impurity levels. |
Technical Specifications of (S)-1-Boc-3-hydroxypiperidine
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | +20.0 to +23.0 deg (c=1, in methanol) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 85.0 to 89.0 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-1-Boc-3-hydroxypiperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-1-Boc-3-hydroxypiperidine
Safety Information of (S)-1-Boc-3-hydroxypiperidine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-1-Boc-3-hydroxypiperidine
Industrial (S)-1-Boc-3-hydroxypiperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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