4-Amino-2-chloro-5-methylpyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 14394-70-8 |
| Product name | 4-Amino-2-chloro-5-methylpyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Amino-2-chloro-5-methylpyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Amino-2-chloro-5-methylpyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Amino-2-chloro-5-methylpyrimidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antitumor agents (e.g., gefitinib analogues) | Used to introduce the pyrimidine ring structure via nucleophilic substitution or coupling reactions, enabling construction of the active pharmaceutical ingredient scaffold |
| Agrochemicals | Intermediate for synthesizing novel fungicides or herbicides | Applied in substitution reactions at the chlorine site or derivatization of the amino functional group to prepare biologically active agrochemical compounds |
| Chemical Research | Organic synthesis building block for nitrogen-containing heterocycles | Employed as a key precursor in palladium-catalyzed cross-coupling, condensation, or cyclization reactions |
Manufacturing Quality Control of 4-Amino-2-chloro-5-methylpyrimidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection for quantification of common solvents (e.g., methanol, acetone, toluene) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and matrix-matched calibration. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of inorganic residue to assess non-volatile inorganic impurities. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating purity and identity via comparison to reference standard. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light and specified viewing conditions. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode to detect acidic/basic impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using light scattering principles to determine D10, D50, D90 values. |
| Organic Volatile Impurities (OVI) | GC-MS | Targeted and untargeted screening using headspace GC coupled with mass spectrometry for identification and quantification of volatile organic contaminants. |
Technical Specifications of 4-Amino-2-chloro-5-methylpyrimidine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Amino-2-chloro-5-methylpyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Amino-2-chloro-5-methylpyrimidine
Safety Information of 4-Amino-2-chloro-5-methylpyrimidine
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4-Amino-2-chloro-5-methylpyrimidine
Industrial 4-Amino-2-chloro-5-methylpyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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