1-BOC-3-AMINOPIPERIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 144243-24-3 |
| Product name | 1-BOC-3-AMINOPIPERIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-BOC-3-AMINOPIPERIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-BOC-3-AMINOPIPERIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-BOC-3-AMINOPIPERIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Organic synthesis intermediate for constructing piperidine-containing active pharmaceutical ingredients (APIs), such as JAK inhibitors and NK1 receptor antagonists | Used as a chiral nitrogen protecting group in multi-step reactions including coupling, reduction, and cyclization; the tert-butoxycarbonyl (Boc) group can be selectively removed under acidic conditions to facilitate subsequent functional group transformations |
| Pharmaceutical R&D | Structural building block in high-throughput screening compound libraries for structure–activity relationship (SAR) studies | Employed as a synthon in solid-phase or solution-phase combinatorial chemistry; aryl and heteroaryl substituents are introduced via cross-coupling reactions such as Suzuki and Buchwald–Hartwig |
| Fine Chemicals | Chiral catalyst ligand precursor | Derivatized to prepare chiral phosphine–nitrogen hybrid ligands or N-heterocyclic carbene precursors for asymmetric hydrogenation and C–N bond formation catalysis |
Manufacturing Quality Control of 1-BOC-3-AMINOPIPERIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities relative to the main peak using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on retention time and peak area. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at specified temperature and concentration to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantification of trace metal contaminants (e.g., Pb, Cd, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration followed by precise weighing of residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually as solid-to-liquid phase change in a calibrated capillary tube. |
| pH of Aqueous Solution | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous suspension or solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to derive volume-based particle size distribution. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms by filtration, membrane transfer to culture media, and colony counting after incubation. |
Technical Specifications of 1-BOC-3-AMINOPIPERIDINE
| Test Item | Specification |
|---|---|
| Appearance | Colorless to yellow liquid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | -15.0 to -25.0 deg (c=1, in methanol) |
| Solubility | Freely soluble in methanol, ethanol, and dichloromethane |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-BOC-3-AMINOPIPERIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-BOC-3-AMINOPIPERIDINE
Packaging of 1-BOC-3-AMINOPIPERIDINE
Industrial 1-BOC-3-AMINOPIPERIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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