China Factory Direct
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| CAS number | 1443-80-7 |
| Product name | 4-Acetylbenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Dye Industry | Synthesis of phthalocyanine dyes | Applied in the synthesis of phthalocyanine blue, phthalocyanine green, and other dyes, involving cyclization to form macrocyclic structures. |
| Pharmaceutical Intermediates | Synthesis of pharmaceutical intermediates | Applied in the synthesis of intermediates for antipyretic-analgesic and anti-inflammatory drugs, typically involving cyclization reactions. |
| Pesticide Industry | Synthesis of fungicides and herbicides | Applied in the synthesis of broad-spectrum fungicides and herbicides, involving oxidation or other chemical transformations. |
| Fine Chemicals | Production of fragrances and electronic chemicals | Applied in the production of fragrances and electronic chemicals, involving esterification or other functionalization reactions. |
| Materials Science | Synthesis of high-performance materials | Applied in the synthesis of polyimides and functional polymers, involving imide ring formation. |
| Synthetic Chemistry | Synthesis of complex organic molecules | Used as an organic building block in the synthesis of diverse complex organic molecules, involving various organic reactions such as SN2, addition, and cyclization. |
| Detection Item | Common Detection Method | Method Overview |
|---|---|---|
| Purity (Content) | High-Performance Liquid Chromatography (HPLC) | Using a reverse-phase C18 column with methanol/water or acetonitrile/water as the mobile phase, and a UV detector (typically at 254 nm or 260 nm). The main component content is quantitatively analyzed by comparing retention time and peak area with that of a standard reference. This method is suitable for precise quantitative analysis of high-purity samples. |
| Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | This method is suitable for qualitative and quantitative analysis of volatile impurities. The sample is derivatized or directly injected, and impurities are identified through characteristic ion fragments detected by mass spectrometry. It can effectively detect by-products or residual solvents generated during synthesis. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR provide detailed molecular structure information, confirming the chemical structure of cyanobenzeneacetone and verifying whether it contains isomers or structural defects. It is commonly used in research and standard substance confirmation. |
| Content Determination (Alternative Method) | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Utilizing the characteristic absorption of cyanobenzeneacetone at specific wavelengths (e.g., 270–280 nm), quantitative analysis is performed via a standard curve method. This method is simple to operate, low-cost, but susceptible to interference from impurities, making it suitable for rough screening or process monitoring. |
| Residual Solvent Detection | Gas Chromatography (GC-FID/MS) | Using headspace injection or direct injection, this method detects residual organic solvents (such as ethanol, acetone, dichloromethane, etc.) generated during synthesis. It complies with ICH Q3A/Q3C requirements, ensuring product safety. |
| Melting Point Determination | Micro Melting Point Apparatus | By observing the melting behavior of the sample during heating, the melting point range (theoretical value approximately 115–118°C) is determined. It can be used for preliminary judgment of purity and crystal structure, serving as an auxiliary detection method. |
| Moisture Content | Karl Fischer Titration (KF) | Using coulometric or volumetric Karl Fischer reagent, this method precisely determines the moisture content in the sample. It is suitable for products sensitive to moisture, ensuring storage stability and reactivity. |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.5% (GC-MS) |
| Melting Point | 78.0–82.0°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.