China Factory Direct
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| CAS number | 14446-47-0 |
| Product name | Thiazolidine, hydrochloride (1:1) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Intermediate for Vitamin B1 (Thiamine) | Serves as a thiazole ring donor in condensation with pyrimidine derivatives to construct the thiazole ring of Vitamin B1. |
| Pharmaceutical Chemicals | Building block for drug synthesis | Used to synthesize thiazole-containing drug molecules or biologically active compounds. |
| Organic Synthesis | Deprotection reagent for acetals/ketals | Catalyzes acid-mediated cleavage of acetal or ketal protecting groups to regenerate carbonyl compounds. |
| Chemical Reagents | Synthesis of heterocyclic compounds | Acts as a bidentate reagent or precursor containing nitrogen and sulfur for constructing thiazole derivatives. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies active ingredient by titration with standardized NaOH solution using phenolphthalein indicator. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric reaction between water and iodine in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by weighing of residual mass. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Heavy Metals | ICP-OES | Simultaneously detects trace metal impurities (e.g., Pb, Cd, Hg) after acid digestion via plasma emission spectroscopy. |
| Related Substances | HPLC-UV | Separates and quantifies structurally related impurities using reversed-phase column and UV detection at 210 nm. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Measures hydrogen ion activity in aqueous solution using calibrated glass electrode and pH meter. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid under controlled heating. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light caused by chiral molecules in solution. |
| Sulfate Impurity | Barium Sulfate Gravimetric Method | Precipitates sulfate as BaSO4 and determines content by weighing the dried precipitate. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Quantifies volatile content by measuring mass loss upon controlled heating under nitrogen atmosphere. |
| Organic Volatile Impurities | Gas Chromatography (GC-FID) | Detects and quantifies residual solvents using capillary column separation and flame ionization detection. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148-152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Conforms to reference standard |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.