China Factory Direct
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| CAS number | 144584-65-6 |
| Product name | 1-BROMO-3-CHLORO-2-FLUOROBENZENE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antitumor agents | Used to construct the core scaffold of pyrimidine or pyridine derivatives |
| Pharmaceuticals | Intermediate for antiviral agents | Used in the synthesis of active pharmaceutical ingredients (APIs) containing fluorine or chlorine substituents |
| Agrochemicals | Intermediate for insecticides | Used to synthesize agrochemical active ingredients featuring halogenated aromatic rings |
| Chemicals | Organic synthesis building block | Employed in Suzuki coupling reactions to construct biaryl compounds |
| Chemicals | Synthesis of functional materials | Incorporated as a monomer to introduce specific halogen functional groups |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities. Typically a colorless to pale yellow liquid or crystalline solid. |
| Assay (Main Component Purity) | Gas Chromatography (GC) | Using capillary columns (e.g., HP-5, DB-5) with an FID detector; qualitative analysis based on retention time, quantitative analysis using peak area normalization. Suitable for volatile organic compounds. |
| High-Performance Liquid Chromatography (HPLC) | Used when thermal instability exists or GC is not suitable; employs reversed-phase C18 column with UV detection (approx. 220–254 nm); purity determined by external standard or normalization method. | |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹⁹F NMR are used to confirm the chemical environments of hydrogen and fluorine atoms in the molecule, verifying correct substitution patterns. |
| Mass Spectrometry (MS) | Uses EI-MS or ESI-MS to detect molecular ion peaks for molecular weight confirmation, and analyzes fragment ions to assist structural identification. | |
| Moisture Content | Karl Fischer Titration | Determines trace amounts of water in samples via electrochemical titration; available as volumetric or coulometric methods. Widely used for water content determination in organic solvents. |
| Residual Solvents | Gas Chromatography (GC) | Detects organic solvents possibly remaining from manufacturing processes (e.g., toluene, ethanol), following pharmacopoeial guidelines or standards such as ICH Q3C. |
| Halogen Content (Cl, Br, F) | Elemental Analysis (EA) or Ion Chromatography (IC) | EA measures weight percentages of elements like C, H, N, Cl to verify molecular composition; IC can determine ionizable halide ions (after appropriate sample pretreatment). |
| Related Substances (Impurities) | GC or HPLC | Detects and quantifies process-related impurities or degradation products by separation from the main peak; gradient elution or programmed temperature ramping often used to improve resolution. |
| Melting Point / Boiling Point | Melting Point Apparatus or Differential Scanning Calorimetry (DSC) | Determines melting point range to assess purity and crystal form consistency; DSC provides more precise phase transition temperature data. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 38.0–42.0°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.