China Factory Direct
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| CAS number | 14470-28-1 |
| Product name | 4-Methoxytriphenylchloromethane |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemistry | Protecting group for nucleosides, nucleotides, and saccharide compounds; used to protect hydroxyl groups during synthesis | Applied as a hydroxyl-protecting reagent in organic synthesis; forms ether linkages via nucleophilic substitution between the chlorine atom and hydroxyl groups, followed by deprotection under mild acidic conditions |
| Organic Synthesis | Amino acid side-chain protection in solid-phase peptide synthesis to prevent side reactions | Reacts with hydroxyl or amino groups of amino acids under inert atmosphere to form stable protecting groups, subsequently removed by acidolysis at the final synthesis stage |
| Materials Science | Intermediate for synthesizing functionalized polymers or dendrimers, enabling introduction of specific functional groups | Participates in polymerization reactions as a monomer or modifying agent; chlorine groups bond to active hydrogen sites to construct molecular frameworks |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., dichloromethane, toluene) using capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on elemental mass-to-charge ratio detection. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate per pharmacopeial standards (e.g., USP <741>). |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of inorganic ash content by high-temperature incineration (500–600 °C) followed by precise weighing of residual residue. |
| Related Substances | HPLC-UV (with gradient elution) | Identification and quantification of structurally related impurities (e.g., triphenylmethanol, desmethyl analogs) using optimized reverse-phase chromatographic separation. |
| Optical Rotation | [α]D Measurement (Polarimetry) | Determination of specific optical rotation at 589 nm using a sodium D-line source to assess chiral purity or absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on angular scattering pattern of laser light through dispersed sample. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measurement of pH in a standardized suspension (e.g., 1% w/v in water) using calibrated glass electrode to detect acidic/basic degradation products. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Quantification of volatile components (e.g., solvates, moisture) by measuring mass loss under controlled heating (e.g., 105 °C, 2 h) per ICH Q5C. |
| Elemental Analysis (C, H, Cl) | Combustion Analysis (CHN/Cl Analyzer) | Quantitative determination of carbon, hydrogen, and chlorine content via high-temperature combustion and gas chromatographic or microcoulometric detection. |
| Microbial Contamination | Membrane Filtration & Plate Count | Enumeration of aerobic mesophilic microorganisms following filtration, membrane transfer to agar media, and colony counting per Ph. Eur. 2.6.12. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-orange solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 128–132°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.