FMOC-D-NVA-OH Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 144701-24-6 |
| Product name | FMOC-D-NVA-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for FMOC-D-NVA-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-D-NVA-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-D-NVA-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | As a chiral amino acid derivative, used to protect D-norvaline residues in peptide synthesis | Serves as a building block for Fmoc protecting groups in solid-phase peptide synthesis (SPPS) |
| Biochemical Research | Used to synthesize custom peptides containing non-natural amino acids for studying protein structure and function | Stepwise coupling and deprotection under the Fmoc strategy |
| Medicinal Chemistry | Involved in developing peptide-based lead compounds for targeted therapeutics or enzyme inhibitors | Fragment coupling and hybrid liquid-phase/solid-phase synthesis based on Fmoc-D-norvaline |
| Diagnostics Reagent Development | Component of antigenic epitopes or labeled peptide sequences for immunoassays | HPLC purification and mass spectrometric characterization following solid-phase peptide synthesis |
Manufacturing Quality Control of FMOC-D-NVA-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 260-280 nm. |
| Chiral Purity | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase with UV detection; enantiomeric excess calculated from peak area ratio. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water in anhydrous methanol-based solvent. |
| Residual Solvents | GC-FID | Headspace or direct injection GC with flame ionization detection; quantification via external calibration curves for common solvents (e.g., DMF, THF, ethyl acetate). |
| Heavy Metals | ICP-MS | Multi-element detection after acid digestion; quantifies metals (e.g., Pb, Cd, Hg, Ni) at trace levels based on mass-to-charge ratio. |
| Residual Palladium | ICP-OES | Quantitative analysis after microwave-assisted acid digestion; detection based on element-specific atomic emission lines. |
| Appearance | Visual Inspection | Assessment under controlled white light against standard color/opacity references; checks for uniformity, discoloration, or foreign particles. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, using calibrated digital apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution; used to confirm identity and chiral integrity. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under specified vacuum and temperature conditions (e.g., 60 C, 2 h, 20 mbar). |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Fmoc-Gly, di-Fmoc-D-Nva, hydrolysis products) using gradient elution and UV detection. |
| pH of Solution | Potentiometric pH Measurement | pH determination of a standardized aqueous or aqueous-methanolic suspension using a calibrated glass electrode and pH meter. |
Technical Specifications of FMOC-D-NVA-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +17.5° to +22.5° (c=1, in DMF) |
| Melting Point | 148°C to 152°C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of FMOC-D-NVA-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-D-NVA-OH
Packaging of FMOC-D-NVA-OH
Industrial FMOC-D-NVA-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply