China Factory Direct
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| CAS number | 144978-35-8 |
| Product name | 1-BOC-D-PYROGLUTAMIC ACID ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as an amino acid protecting group in peptide drug synthesis | Solid-phase peptide synthesis, liquid-phase peptide synthesis |
| Cosmetics | Serves as a base raw material for skin-conditioning or moisturizing agents | Formulation blending |
| Research | Applied in studies of protein structure–function relationships | Biochemical assays, enzyme activity testing |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., ethyl acetate, ethanol) against calibrated standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation to determine trace water content based on stoichiometric reaction with Karl Fischer reagent. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis after acid digestion, detecting metals (e.g., Pb, Cd, Ni) at sub-ppb levels using mass spectrometric detection. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection, referenced to sodium chloride standard. |
| Residue on Ignition | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of inorganic residue to assess inorganic ash content. |
| pH of Solution (1% w/v in Water) | pH Meter | Potentiometric measurement of aqueous solution pH using calibrated glass electrode system. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using controlled heating and visual observation of meniscus movement. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting and white background. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using Mie scattering theory applied to laser diffraction patterns. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (by LC-MS) |
| Optical Rotation | +44.0 to +47.0 deg (c=1, in CHCl3) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68 to 72 °C |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.