1-(2-Hydroxy-5-methylphenyl)ethanone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1450-72-2 |
| Product name | 1-(2-Hydroxy-5-methylphenyl)ethanone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(2-Hydroxy-5-methylphenyl)ethanone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(2-Hydroxy-5-methylphenyl)ethanone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(2-Hydroxy-5-methylphenyl)ethanone
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediate | Serves as a key structural scaffold in the synthesis of anti-allergic, anti-inflammatory, and antitussive drug molecules. |
| Pharmaceuticals | Analgesic synthesis | Used as a precursor in the synthesis of analgesics (e.g., fenamic acid derivatives), participating in condensation reactions. |
| Flavors & fragrances | Fixative and harmonizing agent | Directly incorporated into food-grade or household fragrance formulations, leveraging its vanilla bean- and butter-like odor profile. |
| Chemical synthesis | Organic synthesis intermediate | Undergoes etherification, esterification, or Friedel–Crafts reactions via its phenolic hydroxyl and carbonyl functional groups to construct complex organic molecules. |
| Chemical synthesis | Metal chelating agent | Acts as a ligand precursor for coordination with transition metal ions, enabling preparation of metal–organic frameworks or catalysts. |
| Optoelectronic materials | Photoinitiator raw material | Used to synthesize specific high-efficiency photoinitiator components for ultraviolet-curable coatings and inks. |
Manufacturing Quality Control of 1-(2-Hydroxy-5-methylphenyl)ethanone
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Characteristics | Visual Inspection Method | Observe the sample's color, physical state (e.g., white to off-white crystalline or powder), and presence of foreign matter with the naked eye to determine compliance with quality standards. |
| Identification Test | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
- IR: Measure the infrared absorption spectrum of the sample and compare characteristic absorption peaks with a reference spectrum (e.g., carbonyl C=O at ~1680 cm⁻¹, phenolic O–H at ~3200–3500 cm⁻¹). - HPLC: Compare retention times of test sample and reference standard under specific chromatographic conditions. - ¹H NMR: Analyze chemical shifts and coupling constants of hydrogen atoms to confirm molecular structural features (e.g., methyl, aromatic protons, hydroxyl groups). |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol-water or acetonitrile-water as mobile phase, detected by UV detector (typically at 254 nm or 280 nm). Quantify the main component using external standard method, typically requiring ≥98.0% or according to pharmacopoeial or enterprise specifications. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Perform gradient elution under the same or optimized conditions used for content determination to separate and quantify potential impurities (e.g., starting material residues, oxidation products, by-products). Use area normalization or the main component self-control method with correction factors to control individual and total impurity levels (e.g., individual impurity ≤0.5%, total impurities ≤1.0%). |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Drying Method | Dry the sample at 105°C to constant weight and calculate the percentage of mass loss, used to assess moisture and volatile substance content. Typically requires ≤0.5%. |
| Melting Point | Capillary Melting Point Method | Determine the temperature range from initial melting to complete melting using a melting point apparatus. The typical melting point of 2-hydroxy-5-methylacetophenone is approximately 98–102°C, used to assess purity and consistency. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection GC with FID detection. Detect potentially residual organic solvents (e.g., methanol, ethanol, acetone, dichloromethane) according to ICH Q3C guidelines, ensuring they remain within safe limits. |
| Heavy Metals | Thioacetamide Method or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | - Thioacetamide Method: Colorimetric determination of total heavy metals (expressed as Pb), usually limited to ≤20 ppm. - ICP-MS: High-sensitivity quantification of specific metal elements (e.g., Pb, As, Cd, Hg), suitable for more stringent quality control requirements. |
Technical Specifications of 1-(2-Hydroxy-5-methylphenyl)ethanone
| Test Item | Specification |
|---|---|
| Appearance | Gray crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 52–56°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(2-Hydroxy-5-methylphenyl)ethanone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-(2-Hydroxy-5-methylphenyl)ethanone
Safety Information of 1-(2-Hydroxy-5-methylphenyl)ethanone
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-(2-Hydroxy-5-methylphenyl)ethanone
Industrial 1-(2-Hydroxy-5-methylphenyl)ethanone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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