1-(5-Chloro-2-hydroxyphenyl)ethanone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1450-74-4 |
| Product name | 1-(5-Chloro-2-hydroxyphenyl)ethanone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(5-Chloro-2-hydroxyphenyl)ethanone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(5-Chloro-2-hydroxyphenyl)ethanone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(5-Chloro-2-hydroxyphenyl)ethanone
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antibacterial drug intermediates | Used as a benzyl ketone derivative to construct chlorohydroxy-containing drug molecules, such as intermediates for quinolone antibiotics |
| Pesticides | Synthesis of insecticide and fungicide intermediates | Applied in nucleophilic substitution or acylation reactions to introduce the chlorohydroxybenzyl ketone structure into organophosphorus or heterocyclic compounds |
| Dyes | Synthesis of fluorescent dyes and photosensitizers intermediates | Employed as a photosensitive backbone unit in condensation reactions to form azo- or coumarin-based dyes with ultraviolet absorption properties |
| Chemical Reagents | Synthesis of organic building blocks | Utilized to prepare ligands or functional molecules containing chlorophenyl ketone structures, serving as standard reagents for laboratory coupling reactions |
Manufacturing Quality Control of 1-(5-Chloro-2-hydroxyphenyl)ethanone
| Test Item | Common Analytical Methods | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectrophotometry (IR) | Determines the infrared absorption spectrum of the sample and compares it with reference spectra to confirm the presence of characteristic functional groups (e.g., carbonyl, phenolic hydroxyl, aromatic ring) in 5'-chloro-2'-hydroxyacetophenone. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Uses NMR technology to analyze the chemical shift, coupling constants, and integration area of hydrogen atoms in the molecule, verifying whether the molecular structure matches the expected structure of 5'-chloro-2'-hydroxyacetophenone. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Employs a reversed-phase C18 column with a mobile phase of methanol-water or acetonitrile-water. Detection is performed using a UV detector (typically at 254 nm). The content of the main component is determined by external or internal standard method, offering high sensitivity and good repeatability. |
| Related Substances (Impurity Check) | High-Performance Liquid Chromatography (HPLC) | Uses chromatographic conditions similar to those for the assay, but with an optimized gradient elution program to effectively separate the main peak from potential impurities (e.g., unreacted starting materials, by-products, degradation products). Impurity levels are calculated using the area normalization method or with correction factors. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Drying Method | The sample is dried at a specified temperature (e.g., 105°C) until constant weight is achieved. The percentage weight loss is measured to control moisture and volatile impurities. |
| Melting Point Determination | Capillary Melting Point Method or Digital Melting Point Apparatus | Determines the temperature range from initial melting to complete melting of the sample. The result is compared with literature values (approximately 90–93°C) as an auxiliary indicator of purity and identity. |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace or direct injection with polar or non-polar capillary columns and an FID detector. Quantitative analysis of potentially residual organic solvents (e.g., toluene, ethanol, acetone) is performed according to pharmacopoeia or ICH guidelines. |
| Heavy Metals / Elemental Impurities | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After sample digestion, the method detects levels of harmful elements such as lead, arsenic, cadmium, and mercury to ensure compliance with relevant safety limits (e.g., ICH Q3D). |
Technical Specifications of 1-(5-Chloro-2-hydroxyphenyl)ethanone
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 78–82°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(5-Chloro-2-hydroxyphenyl)ethanone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-(5-Chloro-2-hydroxyphenyl)ethanone
Safety Information of 1-(5-Chloro-2-hydroxyphenyl)ethanone
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-(5-Chloro-2-hydroxyphenyl)ethanone
Industrial 1-(5-Chloro-2-hydroxyphenyl)ethanone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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