China Factory Direct
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| CAS number | 145038-52-4 |
| Product name | FMOC-ASP-OME |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Intermediate for peptide drug synthesis | Used in solid-phase or solution-phase peptide synthesis via Fmoc protection |
| Biopharmaceuticals | Precursor for antibiotic and hormone synthesis | Key component in peptide synthesis, enabling amino acid coupling reactions |
| Chemical Reagents | Intermediate for preparing other organic compounds | Converted into other derivatives via esterification, deprotection, and related chemical reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 268 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., di-FMOC, hydrolyzed derivatives) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., DMF, methanol, dichloromethane) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric determination of water via iodine-sulfur dioxide redox reaction in anhydrous methanol/pyridine medium. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 degrees C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Quantification of palladium catalyst residues following microwave-assisted acid digestion and ICP-MS analysis. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions after aqueous extraction and filtration. |
| pH of Solution | Potentiometric Titration | Measurement of pH in a standardized aqueous suspension (1% w/v) using a calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using Mie scattering theory with automated dispersion. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Residual FMOC-Cl | GC-MS | Detection and quantification of unreacted FMOC-chloride by gas chromatography coupled with mass spectrometric detection. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -19.5 to -18.5 deg (c=1, in DMF) |
| Melting Point | 85 to 89 °C |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.