4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 145069-56-3 |
| Product name | 4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 145069-56-3
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 145069-56-3 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 145069-56-3
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Linker in peptide synthesis | Solid-phase peptide synthesis (SPPS), serving as an acid-labile linker to attach the first amino acid to the resin support. |
| Biopharmaceuticals | Derivatization of Wang resin | Chemical synthesis, bonding the phenoxyacetic acid group in its structure to the polymeric resin backbone. |
| Biopharmaceuticals | Preparation of amino acid derivatives | Fmoc-based protection strategy, used as a protected amino acid linker for synthesizing complex amino acid derivatives. |
Manufacturing Quality Control of 145069-56-3
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., deprotected, hydrolyzed, or isomeric forms) via gradient HPLC separation and UV response. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, DCM, methanol) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pd, Ni, Cu from catalyst residues) using inductively coupled plasma mass spectrometry with isotope dilution. |
| Residual Fmoc Chloride | GC-MS | Detects unreacted 9-fluorenylmethyl chloroformate by gas chromatography coupled to mass spectrometry using selective ion monitoring. |
| Acid Value | Acid-Base Titration | Measures free carboxylic acid content via potentiometric titration with standardized NaOH solution in isopropanol/water mixture. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation using a polarimeter at 20 C and 589 nm to confirm chiral integrity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution by measuring angular variation in laser light scattering intensity. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled high-temperature ashing (750 C) and weighing of the ignited sample. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, incubation, and colony enumeration per USP <61>. |
| pH of Aqueous Suspension | pH Meter | Measures pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode to assess acidic/basic impurity load. |
Technical Specifications of 145069-56-3
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 145069-56-3
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 145069-56-3
Packaging of 145069-56-3
Industrial 145069-56-3 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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