China Factory Direct
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| CAS number | 1452-16-0 |
| Product name | 2-Cyanothiazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antibacterial drug intermediate; used to construct the thiazole ring side chain in cephalosporin antibiotics (e.g., cefazoxime sodium) | Coupled with 7-aminocephalosporanic acid (7-ACA) via acylation, followed by salt formation and purification |
| Agrochemicals | Insecticide and fungicide intermediate; used to synthesize novel thiazole-based agrochemicals | Participates in cyclization, substitution, or coupling reactions to build cyanide-containing thiazole active molecules |
| Organic Synthesis | Multifunctional heterocyclic building block; used to construct sulfur- and nitrogen-containing heterocycles | Acts as an electrophile in Michael additions, cycloadditions, or transition metal-catalyzed cross-coupling reactions |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison with a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine is generated in situ to react stoichiometrically with water; endpoint detected amperometrically. |
| Residue on Ignition | Gravimetric Analysis | Sample is incinerated at 700–800 °C to oxidize organic matter; inorganic residue is weighed after cooling in a desiccator. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion, based on element-specific atomic emission intensities in high-temperature plasma. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation of anions on an ion-exchange column followed by quantitative detection via changes in eluent conductivity. |
| Residual Solvents (e.g., acetonitrile, THF) | Headspace GC-FID | Volatile solvents are equilibrated in headspace vial, then injected into GC for separation and flame ionization detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the solid phase converts to liquid; indicates purity and identity. |
| Appearance (Color & Clarity) | Visual Inspection against Standard Solutions | Comparison of sample solution (e.g., in methanol) with platinum-cobalt color standards and assessment of particulate clarity under controlled lighting. |
| Related Substances | HPLC-UV (Gradient) | Separation and quantification of structurally similar impurities using gradient elution and UV detection; identification via retention time matching with reference standards. |
| Sulfate Impurity | Turbidimetric Method (after BaCl₂ precipitation) | Sulfate reacts with barium chloride in acidic medium to form insoluble BaSO₄; turbidity measured spectrophotometrically at 420 nm. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Hydrogen-ion activity determined using calibrated glass electrode and reference electrode in a saturated aqueous suspension (1% w/v). |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 52-56°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.