PYRIDINE-2-CARBOXAMIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1452-77-3 |
| Product name | PYRIDINE-2-CARBOXAMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for PYRIDINE-2-CARBOXAMIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk PYRIDINE-2-CARBOXAMIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of PYRIDINE-2-CARBOXAMIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of anti-tuberculosis agents (e.g., pyrazinamide) | Serves as a key chemical intermediate for constructing the pyrazine ring scaffold via cyclization or derivatization reactions |
| Pharmaceuticals | Synthesis of anticancer agents | Used to synthesize biologically active molecules or pharmaceutical intermediates containing the picolinamide moiety |
| Pharmaceuticals | Synthesis of anti-inflammatory and antimicrobial agents | Employed as a synthetic building block for introducing specific functional groups |
| Organic Synthesis | Coupling reagent in carbonylation reactions | Participates in palladium-catalyzed C–C coupling reactions (e.g., with aryl halides) to construct α-pyridyl ketone derivatives |
| Agrochemicals | Plant growth regulator or agrochemical intermediate | Applied in synthesizing nitrogen-containing heterocyclic compounds with defined biological activity |
| Chemistry | Substrate or cofactor for enzyme inhibitors | Utilized in biochemical research and enzymological mechanism studies |
| Chemistry | Metal ligand or chelating agent | Forms coordination bonds with metal ions via the pyridyl nitrogen and amide group |
Manufacturing Quality Control of PYRIDINE-2-CARBOXAMIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., 2-pyridinecarboxylic acid, unreacted amine) using gradient HPLC-UV with system suitability validation. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, offering sub-pptr detection limits per ICH Q3D. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using suppressed conductivity detection following aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Assessment of physical state (crystalline powder) and color intensity against platinum-cobalt standards. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content after high-temperature incineration (700–800 °C) and weighing of residual residue. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per EP 2.2.3. |
| Specific Optical Rotation | Polarimetry | Determination of chiral purity (if applicable) using sodium D-line light; 2-pyridylamide is achiral, but method included for batch consistency verification. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersion via light scattering to determine D10, D50, D90 values relevant for formulation handling. |
| Microbial Limits | Membrane Filtration / Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
Technical Specifications of PYRIDINE-2-CARBOXAMIDE
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 128–132°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of PYRIDINE-2-CARBOXAMIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of PYRIDINE-2-CARBOXAMIDE
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Industrial PYRIDINE-2-CARBOXAMIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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