China Factory Direct
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| CAS number | 14521-80-3 |
| Product name | 3-BROMO-1H-PYRAZOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Serves as a key building block in the synthesis of pyrazole-containing drug molecules via coupling reactions (e.g., Suzuki coupling) or nucleophilic substitution, for the development of anticancer, antiviral, and anti-inflammatory agents. |
| Agrochemicals | Agrochemical Intermediate | Used in the synthesis of pyridylpyrazole insecticides (e.g., fipronil analogues) and novel herbicides; bromine substitution or pyridine ring incorporation enhances biological activity. |
| Materials Science | Organic Electrochemical Synthesis Feedstock | Leverages bromine reactivity to construct conjugated molecular frameworks for OLED or organic optoelectronic materials via C–H bond activation or cross-coupling reactions. |
| Organic Synthesis | Functional Group Transformation Reagent | Acts as a bifunctional intermediate, exploiting pyridine ring nucleophilicity and bromine leaving-group ability to enable selective metallation or substitution reactions for constructing complex nitrogen-containing heterocycles. |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a calibrated column and carrier gas. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities by retention time and UV absorbance relative to the main peak. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile solvent residues are vaporized in sealed vials and quantified via GC-FID or GC-MS detection. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine reacts stoichiometrically with water; endpoint detected by current change. |
| Acidity (as HBr) | Acid-Base Titration with NaOH | Neutralization of acidic impurities (e.g., residual HBr) using standardized sodium hydroxide solution and potentiometric or indicator endpoint. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Element-specific detection after acid digestion, based on characteristic atomic emission lines at defined wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Separation of anions on an ion-exchange column and quantitative detection via electrical conductivity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change under controlled heating rate; correlates with crystallinity and purity. |
| Appearance | Visual Inspection (against white/black background) | Assessment of physical state, color, and presence of particulates or discoloration under standardized lighting conditions. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Mass difference before and after high-temperature ashing reflects non-volatile inorganic residue content. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral compounds in solution at specified concentration and path length. |
| Bulk Density | Tap Density Tester (ASTM D1895) | Determined by measuring mass per unit volume after standardized mechanical tapping of a powder sample in a graduated cylinder. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by GC-MS) |
| Melting Point | 62–66 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.