China Factory Direct
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| CAS number | 145224-94-8 |
| Product name | MES monohydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biochemistry and Molecular Biology | Buffering agent | Used to maintain pH stability in reaction systems for applications such as enzyme activity studies and protein purification |
| Pharmaceutical R&D | Cell culture additive | Added to cell culture media as a buffering component to support cell growth and metabolic stability |
| In Vitro Diagnostics | Diagnostic reagent formulation | Employed in in vitro diagnostic reagents to maintain constant pH in the reaction environment, thereby enhancing assay accuracy |
| Life Sciences Research | Electrophoresis buffer component | Provides a stable pH environment during protein or nucleic acid electrophoresis |
| Pharmaceutical Manufacturing | Intermediate processing in drug synthesis | Applied in specific drug synthesis pathways for solubilization or stabilization of intermediates |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Check whether the sample is a white to off-white crystalline powder, free from visible impurities or discoloration. |
| Identification | Infrared Spectroscopy (IR) | Compare the IR spectrum of the sample with that of the standard, confirming characteristic absorption peaks for functional groups such as sulfonic acid and morpholine ring. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze proton chemical shifts in D₂O or DMSO-d₆, comparing with literature or standard spectra to confirm structure. | |
| Content (Purity) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with water-methanol or buffer solution as the mobile phase, UV detection at 210–220 nm, calculate the percentage of the main peak area, typically requiring ≥99.0%. |
| Titration Method (Acid-Base Titration) | Determine content by titrating with sodium hydroxide standard solution, using the strong acidity of the sulfonic acid group, and identifying the endpoint via potentiometry or indicator. | |
| Moisture Content | Karl Fischer Titration | Determine the content of crystalline and free water using coulometric or volumetric methods; usually requires 5.0%–6.5% (theoretical value ≈5.8%). |
| Residue on Ignition (Ash Content) | Ignition Residue Method | Incinerate the sample at high temperature (500–600°C), weigh the residue, and control the residue ≤0.1%. |
| Heavy Metals | Atomic Absorption Spectrometry (AAS) or ICP-MS | Process the sample according to pharmacopoeia methods (e.g., USP/EP), then determine the content of heavy metals such as lead, cadmium, mercury, and arsenic, meeting limits (e.g., ≤10 ppm). |
| Chlorides | Silver Nitrate Titration / Ion Chromatography | Determine chloride ions by precipitation with silver nitrate or use ion chromatography for quantification; control chlorides ≤0.05%. |
| Sulfates | BaCl₂ Turbidity Method | Add barium chloride after acidification of the sample, observe turbidity, and compare with standard solutions; control sulfates ≤0.02%. |
| pH Value (Solution) | pH Meter Measurement | Determine pH of a 1% aqueous solution at 25°C; typically requires a pH range of 5.5–7.0 (buffer performance verification). |
| Solubility | Physical Solubility Test | Observe solubility behavior in water, ethanol, ether, etc.; should be soluble in water, slightly soluble in ethanol, and insoluble in ether. |
| Microbial Limit (if applicable) | Plate Count Method / MPN Method | Detect total aerobic bacteria, molds and yeasts, and *Escherichia coli* according to pharmacopoeia regulations; applicable for pharmaceutical-grade products. |
| Particle Size Distribution (if applicable) | Laser Diffraction / Microscopy | For powdered formulations, measure particle size distribution to ensure flowability and uniformity (e.g., D90 < 100 μm). |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 134–138°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.