China Factory Direct
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| CAS number | 1453-82-3 |
| Product name | Isonicotinamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitubercular drug intermediates | Used as a structural analog of isoniazid derivatives in the development and synthesis of antitubercular agents |
| Chemical Research | Organic synthesis reagent | Applied in the construction of nitrogen-containing heterocyclic compounds, including amide condensation and coupling reactions |
| Pesticides | Intermediate for plant growth regulators | Used to synthesize biologically active pyridine derivatives for pesticide molecular structure optimization |
| Materials Science | Ligand for metal–organic framework (MOF) material preparation | Acts as a nitrogen-containing ligand coordinating with transition metal ions during functional material assembly |
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Compare the sample with standard spectra, and confirm the structure based on characteristic absorption peaks (e.g., amide C=O, N-H, aromatic ring C=C, etc.). |
| Ultraviolet-Visible Spectrophotometry (UV-Vis) | Qualitative identification is performed by utilizing its characteristic absorption peak around 260 nm. | |
| Content Determination | HPLC (High-Performance Liquid Chromatography) | Use a C18 column with methanol-water or buffer salt solution as the mobile phase, detect using a UV detector (around 260 nm), and quantify using the external standard method. |
| UV Spectrophotometry (UV) | Determine absorbance at the maximum absorption wavelength, calculate the content based on the standard curve, suitable for samples with high purity. | |
| Related Substances (Impurities) | HPLC (High-Performance Liquid Chromatography) | Gradient elution separates the main component from impurities, detects degradation products (such as nicotinic acid, by-products, etc.), and calculates the content of each impurity. |
| Dry Loss | Thermogravimetric Analysis (TGA) or Oven Method | Dry the sample at 105°C until constant weight, measure mass loss to assess water and volatile component content. |
| Residual Ash | Residue on Ignition Method | Heat the sample at 500–600°C, weigh the residual ash, and assess inorganic impurity content. |
| Heavy Metals | Atomic Absorption Spectrometry (AAS) or ICP-MS | Dissolve the sample and determine the content of heavy metals such as lead, cadmium, and mercury, which must meet pharmacopoeia limits. |
| Solution Clarity and Color | Visual Color Comparison or Spectrophotometry | Precipitate the sample solution and compare it with standard color solutions to determine if it is clear and colorless or meets the specified color requirements. |
| pH Value | pH Meter Method | Prepare a solution of a certain concentration (e.g., 1%), use a calibrated pH meter to measure its acidity or alkalinity. |
| Melting Point | Capillary Melting Point Method | Determine the melting temperature range using a melting point apparatus (literature value is approximately 129–131°C), used for preliminary identification and purity assessment. |
| Test Item | Specification |
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| Appearance | White to almost white powder or crystals |
| Purity | >=98.5% (HPLC) |
| Melting Point | 129.0 - 133.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.