Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 1454-53-1 |
| Product name | Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a piperidinone derivative for synthesizing active pharmaceutical ingredients (APIs) containing the piperidine moiety, including antihistamines, antipsychotics, and analgesics. |
| Pharmaceutical Chemicals | Remifentanil Synthesis | Used as a key intermediate in the synthesis of the opioid analgesic remifentanil. |
| Pharmaceutical Chemicals | Piperidine Ring Construction | Enables structural modification at the 3- and 4-positions of the piperidine ring via Grignard reactions, reductive amination, or alkylation to construct complex drug molecule scaffolds. |
| Organic Synthesis | Laboratory R&D | Functions as a general-purpose chemical reagent for synthesizing novel heterocyclic compounds and building compound libraries for drug screening. |
Manufacturing Quality Control of Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a reference standard using reversed-phase chromatography and UV detection at 210-230 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents (e.g., ethanol, ethyl acetate, toluene) using capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, Ni) after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration derived from hydrochloride salt. |
| Loss on Drying | Gravimetric Analysis | Measurement of mass loss after drying under controlled temperature and vacuum to assess volatile and moisture content. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP/Ph. Eur. guidelines. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| pH of Aqueous Solution | pH Meter | Measurement of pH in a defined aqueous suspension or solution to verify acidic character consistent with hydrochloride salt form. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using laser scattering to determine D10, D50, D90 values per ISO 13320. |
| Microbial Limits | Membrane Filtration | Quantitative determination of aerobic microbial count and absence of specified pathogens (E. coli, Salmonella) per Ph. Eur. 2.6.12. |
Technical Specifications of Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride
Safety Information of Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride
Industrial Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply