China Factory Direct
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| CAS number | 146093-46-1 |
| Product name | 4-(2-Aminoethyl)-1-Boc-piperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthesis of piperidine-based drug intermediates for anticancer and antipsychotic agents | Used as a key chiral intermediate in multistep syntheses, commonly employing Boc-protecting group strategies to construct the piperidine ring |
| Organic Synthesis | Synthesis of novel heterocyclic compounds and functionalized molecular probes | Functional groups are introduced via condensation or alkylation reactions between the amine group and carboxylic acid derivatives or aldehydes |
| Biopharmaceuticals | Preparation of linkers for targeted therapeutics and molecular conjugates (e.g., ADCs) | Applied as an amino-functionalized carrier, coupled to drug molecules via amide or thioether bonds |
| Materials Science | Development of bioactive smart materials or surface modifiers | Leveraged for polymer modification or nanoparticle surface functionalization, capitalizing on its amphiphilic structure |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase C18 column and calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, DMF, EtOAc) via flame ionization detection after headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine-based reagent reacting stoichiometrically with water. |
| Residual Metals (e.g., Pd, Ni, Fe) | ICP-MS | Quantifies trace metal catalysts and contaminants by plasma ionization and mass spectrometric detection. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation of chiral compound in solution using sodium D-line light to confirm enantiomeric identity and purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant impurities. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing, indicating inorganic salt content. |
| pH (1% w/v aqueous solution) | pH Meter | Measures hydrogen ion activity in aqueous suspension to assess acid/base character and potential degradation. |
| Appearance | Visual Inspection | Evaluates physical state, color, and clarity against established reference standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using angular scattering pattern of laser beam. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.5% (HPLC) |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic mild amine odor |
| Optical Rotation | -2.0 to +2.0 deg (c=1, MeOH) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.