China Factory Direct
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| CAS number | 1461-94-5 |
| Product name | CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemistry | Synthetic intermediate for preparing bioactive cyclobutane derivatives | Complex molecular frameworks constructed via organic synthesis reactions such as esterification, decarboxylation, or cycloaddition |
| Organic Synthesis | Chiral ligand or building block for asymmetric synthesis | Rigid cyclic structure and two carboxyl groups utilized in coordination or coupling reactions |
| Materials Science | Monomer or functional polymer precursor | Cyclobutane moiety incorporated into polymers via condensation or ring-opening polymerization to tailor material properties |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies carboxylic acid groups by titration with standardized NaOH using phenolphthalein or potentiometric endpoint detection. |
| Water Content | Karl Fischer Titration | Measures trace water via iodine-sulfur dioxide reaction in a methanol-based reagent, monitored electrometrically. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic impurities by high-temperature ashing followed by weighing of residual ash. |
| Heavy Metals | ICP-OES | Quantifies metallic impurities (e.g., Pb, Cd, Hg, As) after acid digestion using plasma-excited atomic emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using anion-exchange column with conductivity detection. |
| Related Substances | HPLC-UV | Separates and detects structurally related organic impurities using reversed-phase C18 column and UV detection at 210 nm. |
| Melting Point | Capillary Melting Point Determination | Measures temperature range at which solid transitions to liquid using calibrated capillary apparatus under controlled heating. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles against standard reference under controlled lighting. |
| Solubility in Water | Qualitative Solubility Test | Evaluates dissolution behavior in distilled water at specified temperature and agitation time per USP/EP guidelines. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines acidity/basicity of saturated aqueous solution using calibrated pH electrode and buffer standards. |
| Organic Volatile Impurities | GC-FID | Detects and quantifies residual solvents using gas chromatography with flame ionization detection and internal standard calibration. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Melting Point | 178–182°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Acid Value (mg KOH/g) | 360–375 mg KOH/g |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.