China Factory Direct
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| CAS number | 146137-79-3 |
| Product name | 5-CYANO-2-FLUOROBENZALDEHYDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Pharmaceutical Intermediate | Serves as a key synthetic building block in the synthesis of active pharmaceutical ingredients (APIs) containing benzaldehyde or benzonitrile moieties. |
| Pharmaceutical Industry | Synthesis of Protein Kinase Inhibitors | Leverages the distinct electronic effects of fluorine and cyano groups to construct novel protein kinase inhibitors for anticancer drug development. |
| Agrochemical Industry | Agrochemical Intermediate | Used to synthesize fluorinated benzaldehyde-based insecticides or fungicides, where fluorine enhances lipophilicity and metabolic stability. |
| Organic Synthesis | Specialty Organic Synthesis Feedstock | Enables construction of complex organic molecular frameworks via aldehyde condensation reactions and cyano group transformations (e.g., hydrolysis to carboxylic acid or reduction to amine). |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and identification/quantification of structurally related impurities (e.g., starting materials, intermediates, degradants) using gradient HPLC-UV or high-resolution UPLC-MS. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization detection or mass spectrometry to quantify volatile organic solvents (e.g., DMF, THF, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the reaction of iodine with water in anhydrous pyridine–methanol medium; suitable for low-level moisture determination (<0.1%). |
| Heavy Metals (as Pb) | ICP-MS or AAS | Quantitative determination of elemental impurities (e.g., Pb, Cd, Hg, As) after acid digestion, per ICH Q3D, using inductively coupled plasma mass spectrometry or atomic absorption spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change in a capillary tube under controlled heating rate (e.g., 1 °C/min). |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of physical state (crystalline solid), color (compared to APHA platinum-cobalt standards), and absence of visible particulates or discoloration. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Quantification of chloride ions via suppressed conductivity detection in IC or argentometric titration with silver nitrate endpoint detection. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after incineration at 600–700 °C, expressed as % w/w. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at specified wavelength (e.g., sodium D-line, 589 nm) and temperature to confirm chiral integrity (if applicable; note: compound is achiral, but test may be required for batch consistency). |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference standard |
| Identification (IR) | Conforms to reference standard |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.