Chromium picolinate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 14639-25-9 |
| Product name | Chromium picolinate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Chromium picolinate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Chromium picolinate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Chromium picolinate
| Industry | Application | Process |
|---|---|---|
| Nutritional Supplements | Chromium supplement for blood glucose regulation and improvement of insulin sensitivity | Blended with excipients and compressed into tablets or encapsulated |
| Animal Feed Additives | Promotes animal growth, improves feed conversion efficiency, and enhances immune function | Incorporated into premixes or directly added to finished feed |
| Pharmaceuticals | Adjunctive therapy for type 2 diabetes; supports carbohydrate metabolism | Purified after synthesis and formulated into dosage forms |
| Cosmetics | Added to skincare products for claimed anti-aging or skin health benefits | Emulsified or dissolved with other ingredients prior to incorporation |
| Research Reagents | Experimental material for studies on chromium metabolism or diabetes-related mechanisms | High-purity synthesis and unit-dose packaging |
Manufacturing Quality Control of Chromium picolinate
| Test Item | Common Testing Method | Method Summary |
|---|---|---|
| Chromium Picolinate Content | High-Performance Liquid Chromatography (HPLC) | Using a C18 column, with acetonitrile-water (containing 0.1% formic acid or phosphoric acid) as the mobile phase and UV detection at 254–270 nm. Quantification is performed by external standard method, offering high selectivity and accuracy for the main component. |
| Total Chromium (Cr) Content | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Samples are digested with nitric acid and hydrogen peroxide. AAS measures chromium at a wavelength of 357.9 nm; ICP-MS offers higher sensitivity and is suitable for trace chromium analysis, used to verify whether chromium content meets labeled specifications. |
| Organic Ligand (Picolinic Acid) Content | HPLC or Ultraviolet-Visible Spectrophotometry (UV-Vis) | Free picolinic acid is separated from the chromium complex via HPLC, or its UV absorbance is measured at 265 nm to calculate unbound free ligand levels, thereby assessing complexation efficiency. |
| Moisture Content | Karl Fischer Titration | Utilizes the quantitative reaction of iodine-sulfur dioxide-pyridine-methanol system with water. Water content is determined by electrochemical or volumetric methods to ensure product stability and storage safety. |
| Loss on Drying | Gravimetric Loss on Drying (constant weight at 105°C) | The sample is dried at 105°C until constant weight. The weight loss is calculated to assess residual volatile substances such as solvents or moisture, complying with pharmacopoeial general chapter requirements. |
| Heavy Metal Limits | Atomic Absorption Spectroscopy or ICP-MS | After sample digestion, levels of heavy metals such as lead, cadmium, arsenic, and mercury are determined. Limits are controlled according to standards in the Chinese Pharmacopoeia or USP to ensure product safety. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection is used with an FID detector to measure residual solvents such as ethanol, acetone, and ethyl acetate, ensuring compliance with ICH Q3C permissible limits. |
| Particle Size Distribution (for powder formulations) | Laser Diffraction or Microscopy | Used to evaluate uniformity of powder morphology, ensuring process suitability for subsequent operations such as tablet compression or capsule filling. It is a critical quality attribute in solid dosage forms. |
| Microbial Limits | Total aerobic microbial count, mold and yeast count, and test for specified pathogens (e.g., *Escherichia coli*) | Performed according to microbial limit tests in the Chinese Pharmacopoeia, including total viable aerobic count, mold and yeast count, and testing for specified indicator organisms (e.g., *E. coli*), to ensure microbiological safety. |
| Chromium Species (Trivalent Cr vs Hexavalent Cr) | High-Performance Liquid Chromatography coupled with Inductively Coupled Plasma Mass Spectrometry (HPLC-ICP-MS) | Separates and specifically detects trivalent chromium (chromium picolinate) and toxic hexavalent chromium (Cr(VI)), ensuring absence of carcinogenic Cr(VI) impurities. This is a key safety control parameter. |
Technical Specifications of Chromium picolinate
| Test Item | Specification |
|---|---|
| Appearance | Purple to dark purple crystalline powder |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.3% |
| Odor | Characteristic, mild |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Chromium picolinate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Chromium picolinate
Packaging of Chromium picolinate
Industrial Chromium picolinate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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