(S)-(-)-1-Phenylethyl isocyanate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 14649-03-7 |
| Product name | (S)-(-)-1-Phenylethyl isocyanate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-(-)-1-Phenylethyl isocyanate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-(-)-1-Phenylethyl isocyanate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-(-)-1-Phenylethyl isocyanate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemistry | Chiral derivatizing agent for synthesizing optically active pharmaceutical intermediates | Reacts with amines or alcohols to form chiral ureas or carbamates |
| Organic Synthesis | Construction of chiral molecular frameworks containing isocyanate groups | Introduces chiral centers via nucleophilic addition or cycloaddition reactions |
| Analytical Chemistry | Pre-column derivatization for chiral HPLC to resolve enantiomers | Reacts with target chiral amines/alcohols to generate separable diastereomeric derivatives |
| Materials Science | Synthesis of chiral polyurethanes or functional polymeric materials | Undergoes step-growth polymerization with polyols or polyamines |
Manufacturing Quality Control of (S)-(-)-1-Phenylethyl isocyanate
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state (liquid or solid), transparency, and presence of suspended particles or precipitates. Usually a colorless to pale yellow transparent liquid. |
| Content/Purity | Gas Chromatography (GC) or High-Performance Liquid Chromatography (HPLC) | Determine the content of the main component using GC or HPLC, with quantification by external standard or internal standard methods. Commonly uses non-polar or moderately polar chromatographic columns for separation. |
| Enantiomeric Purity (ee value) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Separate (R) and (S) enantiomers using chiral stationary phase chromatographic columns, calculate enantiomeric excess (ee%), and assess optical purity. |
| Moisture Content | Karl Fischer Titration | Determine trace moisture in the sample using coulometric or volumetric methods, avoiding hydrolysis of isocyanates that could affect quality. |
| Isocyanate Content (NCO%) | Titration (e.g., Di-n-butylamine method) | Add excess di-n-butylamine to react with isocyanate groups, then titrate the remaining amine with standard hydrochloric acid solution to calculate NCO group content. |
| Solvent Residue | Gas Chromatography (GC) | Determine residual organic solvents (e.g., toluene, ethanol) from the production process, complying with ICH Q3C guidelines. |
| Impurity Analysis | GC-MS or LC-MS | Combine with mass spectrometry to identify unknown impurities or degradation products, used for structural confirmation and limit testing. |
| Specific Rotation | Polarimeter Measurement | Determine specific rotation at a specified wavelength (e.g., sodium D line, 589 nm) and temperature to verify its (S)-configuration and optical activity. |
Technical Specifications of (S)-(-)-1-Phenylethyl isocyanate
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% |
| Optical Rotation | -39.0 to -41.0 deg (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.545–1.549 |
| Odor | Characteristic pungent odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-(-)-1-Phenylethyl isocyanate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-(-)-1-Phenylethyl isocyanate
Safety Information of (S)-(-)-1-Phenylethyl isocyanate
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of (S)-(-)-1-Phenylethyl isocyanate
Industrial (S)-(-)-1-Phenylethyl isocyanate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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