5-(4-Bromophenyl)-4,6-dichloropyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 146533-41-7 |
| Product name | 5-(4-Bromophenyl)-4,6-dichloropyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-(4-Bromophenyl)-4,6-dichloropyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-(4-Bromophenyl)-4,6-dichloropyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Serves as a key intermediate in the synthesis of tyrosine kinase inhibitor anticancer drugs, such as dasatinib | Used in pharmaceutical synthesis to construct the core drug structure via functionalization reactions, including Suzuki coupling |
| Agrochemicals | Serves as an intermediate for synthesizing novel insecticides or fungicides, enabling construction of pyrimidine-ring-containing bioactive molecules | In agrochemical molecular design, its halogen atoms (Br, Cl) serve as reactive sites for nucleophilic substitution or metal-catalyzed coupling reactions |
| Materials Science | Serves as an organic building block for preparing electron-transport or host materials in organic light-emitting diodes (OLEDs) | Used to construct conjugated molecular systems with tailored optoelectronic properties via polymerization or linkage with other aromatic compounds at its reactive sites |
Manufacturing Quality Control of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
| Test Item | Common Testing Method | Method Description |
|---|---|---|
| Structure Confirmation | Nuclear Magnetic Resonance (NMR) Spectroscopy | Analyze hydrogen and carbon atoms' chemical shifts using ¹H NMR and ¹³C NMR to confirm molecular structure and substitution positions. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase column with a UV detector (e.g., 254 nm) to quantify the main component's purity and separate and detect related impurities. |
| Impurity Content | HPLC or UPLC (Gradient Elution) | Employ gradient elution programs to enhance impurity separation, combined with standard substances or area normalization for quantifying known/unknown impurities. |
| Content Determination | HPLC External Standard Method | Establish a calibration curve using a known concentration of standard substance to quantify the absolute content of the target compound in the sample via external standard method. |
| Melting Point Determination | Capillary Melting Point Apparatus | Determine the melting temperature range of the compound as a physical constant to assist in assessing purity and crystalline consistency. |
| Water Content | Karl Fischer Titration | Determine trace water content in the sample using coulometric or volumetric methods to ensure compliance with loss on drying or moisture limits. |
| Residual Solvents | Gas Chromatography (GC-FID/HS-GC) | Use headspace injection or direct injection with a capillary column to separate and detect residual organic solvents (e.g., toluene, DMF, etc.) using FID. |
| Heavy Metals/Elemental Impurities | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detect trace metal elements (e.g., Pd, Cu, Ni, etc.) to evaluate catalyst residues or inorganic impurities introduced during production. |
| Crystallinity Analysis | X-ray Powder Diffraction (XRPD) | Confirm whether the solid form is the target crystal type by comparing diffraction patterns to avoid polymorphism affecting stability or solubility. |
| Loss on Drying | Oven Drying Method (105°C) | Weigh the mass difference before and after drying the sample at a specified temperature to assess volatile substances or adsorbed water content. |
Technical Specifications of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 148–152°C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
Safety Information of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
Industrial 5-(4-Bromophenyl)-4,6-dichloropyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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