BENZYL (2-OXO-2-PHENYLETHYL)CARBAMATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 146553-06-2 |
| Product name | BENZYL (2-OXO-2-PHENYLETHYL)CARBAMATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BENZYL (2-OXO-2-PHENYLETHYL)CARBAMATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BENZYL (2-OXO-2-PHENYLETHYL)CARBAMATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BENZYL (2-OXO-2-PHENYLETHYL)CARBAMATE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral auxiliary for introducing chiral centers in asymmetric synthesis, particularly in constructing β-amino acid derivatives and drug molecules containing β-aminol structures | Used as a chiral carbamate protecting group; undergoes diastereoselective addition with organolithium or Grignard reagents at low temperature, followed by hydrolysis or reduction to yield optically pure β-aminols or β-amino acids |
| Pharmaceuticals | Key chiral intermediate in the synthesis of anticoagulants (e.g., apixaban analogues) and protease inhibitors | Provides a configurationally stable α-methoxy-N-methylamide chiral building block in multi-step syntheses—including palladium-catalyzed cross-coupling and reductive amination—to ensure stereochemical integrity of the final API |
Manufacturing Quality Control of BENZYL (2-OXO-2-PHENYLETHYL)CARBAMATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and calculation of enantiomeric excess (ee). |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., methanol, THF, ethyl acetate) against calibration standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Residual Palladium | ICP-OES | Determination of palladium residue (e.g., from catalytic hydrogenation) by inductively coupled plasma optical emission spectroscopy. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient HPLC with UV detection and reference standards where available. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a digital polarimeter at specified temperature and concentration in defined solvent. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition analysis by controlled heating of sample in capillary tube; endpoint recorded as range of solid-to-liquid transition. |
| Loss on Drying | Gravimetric Method | Weight loss measured after drying under specified vacuum/temperature conditions, indicating volatile and moisture content. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a standardized aqueous suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
Technical Specifications of BENZYL (2-OXO-2-PHENYLETHYL)CARBAMATE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Optical Rotation | +15.0° to +17.0° (c=1, in CHCl3) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BENZYL (2-OXO-2-PHENYLETHYL)CARBAMATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of BENZYL (2-OXO-2-PHENYLETHYL)CARBAMATE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of BENZYL (2-OXO-2-PHENYLETHYL)CARBAMATE
Industrial BENZYL (2-OXO-2-PHENYLETHYL)CARBAMATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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