China Factory Direct
|
|
| CAS number | 14676-01-8 |
| Product name | 3-(Boc-amino)-3-phenylpropionic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | As an amino acid derivative intermediate for synthesizing protease inhibitors and peptide-based drugs | Used in solid-phase or solution-phase peptide synthesis via condensation after carboxylic acid activation of Boc-protected 3-phenylalanine |
| Chemical Synthesis | For constructing complex organic molecular frameworks containing phenyl and tert-butoxycarbonyl groups | Employed as a chiral building block in asymmetric synthesis, participating in coupling reactions with electrophiles or metal catalysts |
| Biochemical Research | Used as a model compound to study the relationship between peptide conformation and biological activity | Applied in enzyme substrate or inhibitor design by introducing phenylalanine analogues via N-terminal Boc protection strategy |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-220 nm, comparing peak area to a reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against qualified reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., THF, DMF, EtOAc) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Quantification of elemental impurities (e.g., Pb, Cd, Ni, Cu) after acid digestion, using mass spectrometry for multi-element detection at sub-pptr levels. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions after aqueous extraction and filtration. |
| Residual Boc Reagent | GC-FID | Direct or derivatized GC-FID analysis to detect and quantify residual di-tert-butyl dicarbonate (Boc2O) or tert-butanol. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20-25 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, indicating crystallinity and purity. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under controlled temperature and vacuum, reflecting volatile content and moisture. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined aqueous suspension (e.g., 1% w/v) to assess acidic/basic impurities affecting stability. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using light scattering to determine D10, D50, D90 values per ISO 13320. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148-152°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.