China Factory Direct
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| CAS number | 1468-39-9 |
| Product name | ISOVALERIC ANHYDRIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeFood GradeCosmetic Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Cosmetics | Fragrance additive | Used as a fragrance component in perfume and cosmetic formulations |
| Food industry | Food flavoring | Applied in food flavor production to impart fruity notes |
| Pharmaceuticals | Synthetic drug intermediate | Employed in the synthesis of certain pharmaceuticals or intermediates |
| Chemical industry | Synthetic resins and polymers | Utilized as a raw material in polyester resin synthesis |
| Fine fragrance industry | Fragrance compounding | Applied in fragrance formulation to enhance product aroma |
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection + Physical Property Measurement | Observe color and state (typically colorless to slightly yellow liquid), and measure physical parameters such as boiling point, density, refractive index, etc., in compliance with pharmacopoeial or company specifications. |
| Purity (Main Component Content) | Gas Chromatography (GC) | Separate isovaleric anhydride and impurities using a capillary column (e.g., DB-5 or HP-INNOWAX), and quantify using a Flame Ionization Detector (FID). The main component content is calculated by area normalization or internal standard method. |
| Water Content | Karl Fischer Titration | Utilize the iodine-sulfur dioxide-pyridine-methanol system for quantitative reaction with water. Measure trace moisture via electrochemical or volumetric Karl Fischer titration, with water content controlled at ≤0.1%. |
| Acid Value (Free Acid) | Titration Method (Alkaline Titration) | Titrate free isovaleric acid in the sample with standardized sodium hydroxide solution, using phenolphthalein as indicator. Calculate acid value (mg KOH/g) to reflect degree of hydrolysis. |
| Impurity Profile (Organic Impurities) | Gas Chromatography-Mass Spectrometry (GC-MS) | After GC separation, use MS for structural identification to detect potential impurities such as isovaleric acid, isovalanol, dimers, etc., supporting control of impurity limits. |
| Melting Point / Boiling Point | Boiling Point Apparatus / Melting Point Analyzer (if solid) | Since isovaleric anhydride is a liquid, boiling point determination (typical range: 170–175°C) is commonly used to verify purity and batch consistency. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After ashing or digestion of samples, determine residual heavy metals such as lead, cadmium, mercury, and arsenic. Comply with ICH Q3D or pharmacopoeial limits (e.g., ≤10 ppm). |
| Solvent Residuals | Headspace Gas Chromatography (HS-GC) | Detect possible residual organic solvents (e.g., ethanol, acetone, diethyl ether) from manufacturing processes according to ICH Q3C guidelines. |
| Stability (Hydrolysis Tendency) | GC Analysis After Hydrolysis | Mix sample with water and incubate; periodically take samples and analyze by GC for generated isovaleric acid. Assess hydrolytic stability to inform storage condition recommendations. |
| Test Item | Specification |
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| Appearance | Colorless to almost colorless clear liquid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Refractive Index (n20/D) | 1.400 - 1.405 |
| Relative Density (20°C/25°C) | 0.920 - 0.935 g/cm³ |
| Acid Value (mg KOH/g) | <=1.0 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.